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一种用于验证放射治疗剂量的新型简易体模。

A novel simple phantom for verifying the dose of radiation therapy.

作者信息

Lee J H, Chang L T, Shiau A C, Chen C W, Liao Y J, Li W J, Lee M S, Hsu S M

机构信息

Health Physics Division, Institute of Nuclear Energy Research, Longtan 325, Taiwan.

Department of Radiation Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei 112, Taiwan ; Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 112, Taiwan.

出版信息

Biomed Res Int. 2015;2015:934387. doi: 10.1155/2015/934387. Epub 2015 Mar 26.

Abstract

A standard protocol of dosimetric measurements is used by the organizations responsible for verifying that the doses delivered in radiation-therapy institutions are within authorized limits. This study evaluated a self-designed simple auditing phantom for use in verifying the dose of radiation therapy; the phantom design, dose audit system, and clinical tests are described. Thermoluminescent dosimeters (TLDs) were used as postal dosimeters, and mailable phantoms were produced for use in postal audits. Correction factors are important for converting TLD readout values from phantoms into the absorbed dose in water. The phantom scatter correction factor was used to quantify the difference in the scattered dose between a solid water phantom and homemade phantoms; its value ranged from 1.084 to 1.031. The energy-dependence correction factor was used to compare the TLD readout of the unit dose irradiated by audit beam energies with (60)Co in the solid water phantom; its value was 0.99 to 1.01. The setup-condition factor was used to correct for differences in dose-output calibration conditions. Clinical tests of the device calibrating the dose output revealed that the dose deviation was within 3%. Therefore, our homemade phantoms and dosimetric system can be applied for accurately verifying the doses applied in radiation-therapy institutions.

摘要

负责核实放射治疗机构所输送剂量是否在授权限值内的组织采用标准的剂量测量方案。本研究评估了一种自行设计的用于核实放射治疗剂量的简易审计体模;描述了体模设计、剂量审计系统和临床试验。热释光剂量计(TLD)用作邮政剂量计,并制作了可邮寄的体模用于邮政审计。校正因子对于将体模的TLD读出值转换为水中吸收剂量很重要。体模散射校正因子用于量化固体水体模与自制体模之间散射剂量的差异;其值范围为1.084至1.031。能量依赖性校正因子用于比较审计束能量照射的单位剂量在固体水体模中的TLD读出值与(60)Co的情况;其值为0.99至1.01。设置条件因子用于校正剂量输出校准条件的差异。对剂量输出校准装置的临床试验表明剂量偏差在3%以内。因此,我们的自制体模和剂量测量系统可用于准确核实放射治疗机构所施用的剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fabb/4391650/e0c7b385b119/BMRI2015-934387.001.jpg

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