Siu K K, Li Rever, Lam S Y
Department of Paediatrics, Kwong Wah Hospital, Yaumatei, Hong Kong.
Department of Paediatrics, Tuen Mun Hospital, Tuen Mun, Hong Kong.
Hong Kong Med J. 2015 Apr;21(2):172-4. doi: 10.12809/hkmj144237.
This report demonstrates pulmonary haemorrhage as a differential cause of anaemia. Idiopathic pulmonary hemosiderosis is a rare disease in children; it is classically described as a triad of haemoptysis, pulmonary infiltrates on chest radiograph, and iron-deficiency anaemia. However, anaemia may be the only presenting feature of idiopathic pulmonary hemosiderosis in children due to occult pulmonary haemorrhage. In addition, the serum ferritin is falsely high in idiopathic pulmonary hemosiderosis which increases the diagnostic difficulty. We recommend that pulmonary haemorrhage be suspected in any child presenting with iron-deficiency anaemia and persistent bilateral pulmonary infiltrates.
本报告表明肺出血是贫血的一个鉴别病因。特发性肺含铁血黄素沉着症在儿童中是一种罕见疾病;其典型表现为咯血、胸部X光片上的肺部浸润和缺铁性贫血三联征。然而,由于隐匿性肺出血,贫血可能是儿童特发性肺含铁血黄素沉着症的唯一表现特征。此外,特发性肺含铁血黄素沉着症患者的血清铁蛋白假性升高,这增加了诊断难度。我们建议,对于任何出现缺铁性贫血和持续性双侧肺部浸润的儿童,都应怀疑有肺出血。