用于免缝合胃切口手术的贻贝启发式纳米纤维片材。
Mussel-inspired nanofibrous sheet for suture-less stomach incision surgery.
作者信息
Jiang J, Wan W, Ge L, Bu S, Zhong W, Xing M
机构信息
Department of Mechanical Engineering, University of Manitoba, Winnipeg MB, R3T 2N2, Canada.
出版信息
Chem Commun (Camb). 2015 May 21;51(41):8695-8. doi: 10.1039/c5cc01898f.
PMID:25912340
Abstract
We report a dopamine-based crosslinker-conjugated gelatin/polycaprolactone nanofibrous sheet. The nanosheet was then employed to treat stomach incisions without sutures during surgery. The mussel-inspired nanosheets, combining the advantages adhesion and tissue repair, show promise for use in treatments of fragile tissues and to avoid suture-caused stress concentration.
摘要
我们报道了一种基于多巴胺的交联剂共轭明胶/聚己内酯纳米纤维片。然后将该纳米片用于手术期间无需缝合的胃部切口治疗。受贻贝启发的纳米片结合了粘附和组织修复的优点，在治疗脆弱组织以及避免缝合引起的应力集中方面显示出应用前景。
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