Hajós F, Kálmán M
Department of Anatomy and Histology, University of Veterinary Science, Budapest, Hungary.
Exp Brain Res. 1989;78(1):164-73. doi: 10.1007/BF00230695.
The topographical mapping of glial fibrillary acidic protein (GFAP)-immunoreactivity was performed in coronal serial sections of the rat mesencephalon, rhombencephalon and spinal cord. Relative to a background of poor or moderate overall staining of the mesencephalon, the interpeduncular nucleus, substantia nigra and the periaqueductal grey matter were prominent by their intense GFAP-immunoreactivity. The pons and particularly the medulla contained more GFAP-labelled elements compared with the mesencephalon. The spinal trigeminal nucleus and Rolando substance were distinguished by their intense staining. Large fibre tracts were usually poor in immunoreactive GFAP. In a concluding discussion, findings relevant to the GFAP-mapping of the whole rat CNS are evaluated with regard to possible reasons underlying the observed differential distribution of GFAP-immunoreactivity.
在大鼠中脑、后脑和脊髓的冠状连续切片上进行了胶质纤维酸性蛋白（GFAP）免疫反应性的地形图绘制。相对于中脑整体染色较弱或中等的背景，脚间核、黑质和导水管周围灰质因其强烈的GFAP免疫反应性而突出。与中脑相比，脑桥尤其是延髓含有更多GFAP标记的成分。三叉神经脊束核和罗兰多质因其强烈的染色而得以区分。大纤维束通常GFAP免疫反应性较弱。在最后的讨论中，针对观察到的GFAP免疫反应性差异分布的可能原因，对与整个大鼠中枢神经系统GFAP图谱相关的研究结果进行了评估。
