Mahler Leslie A, Ramig Lorraine O, Fox Cynthia
aDepartment of Communicative Disorders, University of Rhode Island, Kingston, Rhode Island bUniversity of Colorado, Boulder, Colorado cColumbia University, New York, New York dNational Center for Voice and Speech, Denver, Colorado, USA.
Curr Opin Otolaryngol Head Neck Surg. 2015 Jun;23(3):209-15. doi: 10.1097/MOO.0000000000000151.
Voice and speech impairments are present in nearly 90% of people with Parkinson disease and negatively impact communication and quality of life. This review addresses the efficacy of Lee Silverman Voice Treatment (LSVT) LOUD to improve vocal loudness (as measured by vocal sound pressure level vocSPL) and functional communication in people with Parkinson disease. The underlying physiologic mechanisms of Parkinson disease associated with voice and speech changes and the strength of the current treatment evidence are discussed with recommendations for best clinical practice.
Two randomized control trials demonstrated that participants who received LSVT LOUD were significantly better on the primary outcome variable of improved vocSPL posttreatment than alternative and no treatment groups. Treatment effects were maintained for up to 2 years. In addition, improvements have been demonstrated in associated outcome variables, including speech rate, monotone, voice quality, speech intelligibility, vocal fold adduction, swallowing, facial expression and neural activation. Advances in technology-supported treatment delivery are enhancing treatment accessibility.
Data support the efficacy of LSVT LOUD to increase vocal loudness and functional communication in people with Parkinson disease. Timely intervention is essential for maximizing quality of life for people with Parkinson disease.
近90%的帕金森病患者存在嗓音和言语障碍,这对交流及生活质量产生负面影响。本综述探讨李·西尔弗曼嗓音治疗(LSVT)大音量疗法对提高帕金森病患者嗓音响度(通过嗓音声压级vocSPL测量)及功能性交流的疗效。讨论了与嗓音和言语变化相关的帕金森病潜在生理机制以及当前治疗证据的力度,并给出最佳临床实践建议。
两项随机对照试验表明,接受LSVT大音量疗法的参与者在治疗后嗓音声压级改善这一主要结局变量上,显著优于替代疗法组和未治疗组。治疗效果可持续长达2年。此外,在相关结局变量方面也有改善,包括语速、语调单一、嗓音质量、言语清晰度、声带内收、吞咽、面部表情及神经激活。技术支持下的治疗方式进展正提高治疗的可及性。
数据支持LSVT大音量疗法对提高帕金森病患者嗓音响度及功能性交流的疗效。及时干预对于最大化帕金森病患者的生活质量至关重要。