专为免疫分析形式设计的增强型灵敏洛夫波表面声波传感器。
Enhanced sensitive love wave surface acoustic wave sensor designed for immunoassay formats.
作者信息
Puiu Mihaela, Gurban Ana-Maria, Rotariu Lucian, Brajnicov Simona, Viespe Cristian, Bala Camelia
机构信息
LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.
Department of Analytical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.
出版信息
Sensors (Basel). 2015 May 5;15(5):10511-25. doi: 10.3390/s150510511.
We report a Love wave surface acoustic wave (LW-SAW) immunosensor designed for the detection of high molecular weight targets in liquid samples, amenable also for low molecular targets in surface competition assays. We implemented a label-free interaction protocol similar to other surface plasmon resonance bioassays having the advantage of requiring reduced time analysis. The fabricated LW-SAW sensor supports the detection of the target in the nanomolar range, and can be ultimately incorporated in portable devices, suitable for point-of-care testing (POCT) applications.
我们报告了一种用于检测液体样品中高分子量靶标的洛夫波表面声波（LW-SAW）免疫传感器，该传感器也适用于表面竞争分析中的低分子靶标检测。我们实施了一种无标记相互作用方案，类似于其他表面等离子体共振生物测定法，具有所需分析时间减少的优点。所制造的LW-SAW传感器支持在纳摩尔范围内检测靶标，并最终可集成到适用于即时检验（POCT）应用的便携式设备中。
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