Momeni Ali, Rahmani Fereidoon, Nasri Hamid
Nephrologist, Department of Nephrology, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Infectious Disease Specialist, Department of Infectious Diseases, Shahrekord University of Medical Sciences , Shahrekord, Iran .
J Clin Diagn Res. 2015 Mar;9(3):OD03-4. doi: 10.7860/JCDR/2015/11483.5666. Epub 2015 Mar 1.
Focal segmental sclerosis (FSGS) is a common cause of idiopathic nephrotic syndrome in the adult population. A patient aged 48- year-old was admitted for evaluation of azotemia. Renal biopsy showed tip lesion FSGS and acute tubular necrosis. After methyl prednisolone pulse therapy, partial remission occurred, and he was stable with oral prednisolone and cyclosporine. Few months later two serious complications including lung and brain abscess occurred. We describe a case of FSGS with lung and brain abscess, who responded to medical management.
局灶节段性肾小球硬化(FSGS)是成人特发性肾病综合征的常见病因。一名48岁患者因氮质血症入院评估。肾活检显示为顶端病变型FSGS和急性肾小管坏死。甲基强的松龙冲击治疗后,病情部分缓解,患者口服强的松龙和环孢素病情稳定。几个月后,出现了包括肺脓肿和脑脓肿在内的两种严重并发症。我们描述了一例患有肺脓肿和脑脓肿的FSGS病例,该病例对药物治疗有反应。