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急诊科危重症患者的预后及灌注指数测量的价值:一项横断面研究。

Prognosis of Critically ill patients in the ED and value of perfusion index measurement: a cross-sectional study.

作者信息

Oskay Alten, Eray Oktay, Dinç Selcan Enver, Aydın Alp Giray, Eken Cenker

机构信息

Denizli State Hospital, Department of Emergency Medicine, Denizli, Turkey.

Akdeniz University Hospital, Department of Emergency Medicine, Dumlupinar Bulvari 07070, Antalya, Turkey.

出版信息

Am J Emerg Med. 2015 Aug;33(8):1042-4. doi: 10.1016/j.ajem.2015.04.033. Epub 2015 Apr 24.

Abstract

OBJECTIVE

Critically ill patients have high mortality and admission rates requiring early recognition and a rapid management. In the present study, we evaluated the prognostic parameters in these patients and the value of perfusion index measurement as a novel tool for accomplishing emergency department (ED) triage.

METHODS

Seven hundred seventy patients admitted to the critical care area of the ED in a month composed the study population. Perfusion index and vital signs (blood pressure, pulse rate, body temperature, pulse oximeter, and respiration rate) of the study patients were recorded to the study form. The communication data, admitting time, comorbidities, capillary refilling time, and blood gas analysis findings if obtained were recorded. Outcome of patients at the end of the ED period such as discharge, admission to the hospital, and death were also recorded. Outcome of patients at 15th and 30th days was identified by telephone call follow-up or from hospital records.

RESULTS

Two hundred seventy-eight patients (36.1%) were admitted to the hospital, 454 patients (59%) were discharged, 3 patients (0.4%) died in the ED, 25 patients (3.2%) were transferred to another hospital, and 10 patients (1.3%) refused treatment and left the ED. Sixty patients (7.8%), 39 (5.1%) of whom had died in 15 days' period, were dead at the end of 30-day follow-up period. Respiratory rate and pulse oximetry were significant parameters in hospital admission. Systolic blood pressure, diastolic blood pressure, pulse rate, respiratory rate, pulse oximetry, lactate levels in blood gas analysis, and ED length of stay were significant variables in 30-day mortality rate. Patients who were admitted to the hospital had higher rates of fever and diabetes. Patients who had died in the 30-day follow-up period had higher rates of diabetes and malignancy. In logistic regression analysis, the predictors of hospital admission were hypotension, fever, and pulse oximetry, whereas the predictors of 30-day mortality were systolic blood pressure, respiratory rate, pulse oximetry, and presence of malignancy.

CONCLUSIONS

Perfusion index as a novel triage instrument was found to be an insignificant tool in predicting hospital admission and mortality of critically ill patients in the ED. However, diabetes and malignancy were found to be independent factors in determining the prognosis of these patients in addition to vital signs and should be considered by ED physicians either in triage field or inside the ED.

摘要

目的

重症患者死亡率和住院率较高,需要早期识别和快速处理。在本研究中,我们评估了这些患者的预后参数以及灌注指数测量作为急诊科(ED)分诊新工具的价值。

方法

一个月内入住急诊科重症监护区的770例患者构成研究人群。将研究患者的灌注指数和生命体征(血压、脉搏率、体温、脉搏血氧饱和度和呼吸频率)记录到研究表格中。记录沟通数据、入院时间、合并症、毛细血管再充盈时间以及血气分析结果(若有)。还记录了患者在急诊科结束时的结局,如出院、住院和死亡情况。通过电话随访或医院记录确定患者在第15天和第30天的结局。

结果

278例患者(36.1%)住院,454例患者(59%)出院,3例患者(0.4%)在急诊科死亡,25例患者(3.2%)转至其他医院,10例患者(1.3%)拒绝治疗并离开急诊科。60例患者(7.8%)在30天随访期结束时死亡,其中39例(5.1%)在15天内死亡。呼吸频率和脉搏血氧饱和度是住院的重要参数。收缩压、舒张压、脉搏率、呼吸频率、脉搏血氧饱和度、血气分析中的乳酸水平以及急诊科住院时间是30天死亡率的重要变量。住院患者发热和糖尿病的发生率较高。在30天随访期内死亡的患者糖尿病和恶性肿瘤的发生率较高。在逻辑回归分析中,住院的预测因素是低血压、发热和脉搏血氧饱和度,而30天死亡率的预测因素是收缩压、呼吸频率、脉搏血氧饱和度和恶性肿瘤的存在。

结论

灌注指数作为一种新的分诊工具,在预测急诊科重症患者的住院率和死亡率方面被发现是一个无显著意义的工具。然而,除生命体征外,糖尿病和恶性肿瘤被发现是决定这些患者预后的独立因素,急诊科医生在分诊现场或急诊科内均应予以考虑。

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