研究对患有痴呆行为和心理症状的住院患者按需给药的趋势。
Examining trends in the administration of "as needed" medications to inpatients with behavioral and psychological symptoms of dementia.
作者信息
Neumann Robert D, Faris Peter, Klassen Richard
机构信息
Centennial Centre for Mental Health and Brain Injury, Alberta Health Services, Ponoka, Alberta, Canada
Alberta Health Services, Calgary, Alberta, Canada Department of Community Health Science, University of Calgary, Calgary, Alberta, Canada.
出版信息
Am J Alzheimers Dis Other Demen. 2015 May;30(3):247-56. doi: 10.1177/1533317515585924.
RATIONALE
The use of "pro re nata" (PRN) medication in patients with behavioral and psychological symptoms of dementia (BPSD) is common but may be a source of inappropriate medication administration.
OBJECTIVE
To identify trends in the administration of PRN medications to inpatients with BPSD.
METHODS
Retrospective chart audits were completed on inpatients with dementia who had PRN medications prescribed for aggression, agitation, or insomnia. Data collected included age, sex, time of day, day of week, medication used, and dementia diagnosis. Additionally, data regarding administration of ranged doses and concurrent use with regularly prescribed medications of the same class were collected.
RESULTS
A total of 170 inpatients with dementia were included. Over 50 346 bed days, 4000 PRNs were administered. Individuals were more likely to receive a PRN if they were younger, shortly after shift change, in the evening, or during the weekend. If a ranged dose is provided they are more likely to receive the higher dose. If they are receiving regularly scheduled medication from the same class, there is risk of double dosing.
理论依据
在患有痴呆症行为和心理症状（BPSD）的患者中使用“必要时”（PRN）药物很常见，但可能是不适当用药的一个来源。
目的
确定对患有BPSD的住院患者使用PRN药物的趋势。
方法
对为攻击、激越或失眠开具PRN药物的痴呆住院患者进行回顾性病历审核。收集的数据包括年龄、性别、一天中的时间、一周中的日期、使用的药物以及痴呆诊断。此外，还收集了关于不同剂量给药以及与同一类常规处方药物同时使用的数据。
结果
共纳入170例痴呆住院患者。在超过50346个住院日期间，共给予了4000次PRN药物。年龄较小、交接班后不久、晚上或周末的患者更有可能接受PRN药物治疗。如果提供了不同剂量，他们更有可能接受较高剂量。如果他们正在接受同一类别的定期用药，则存在重复给药的风险。
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