Djoussé Luc, Petrone Andrew B, Hickson DeMarc A, Talegawkar Sameera A, Dubbert Patricia M, Taylor Herman, Tucker Katherine L
Brigham and Women's Hospital, Boston, MA, USA; Boston Veterans Affairs Healthcare System, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Brigham and Women's Hospital, Boston, MA, USA.
Clin Nutr. 2016 Jun;35(3):679-84. doi: 10.1016/j.clnu.2015.04.016. Epub 2015 Apr 30.
BACKGROUND & AIMS: Type 2 diabetes (DM) disproportionally affects African Americans. Data on the association between egg consumption and risk of DM are sparse. We sought to examine whether egg consumption is associated with the prevalence and incidence of DM among African Americans.
We analyzed baseline data from 4568 participants of the Jackson Heart Study. Egg consumption was obtained using a food frequency questionnaire designed for this population. We used generalized estimating equations to calculate adjusted prevalence ratios of DM and Cox regression to estimate hazard ratios of DM with corresponding 95% confidence intervals (CI).
The average age was 55 ± 13 years and 64% of subjects were women. The median frequency of egg consumption was 2/week for men and 1/week for women. The prevalence of DM was 22% overall (21% of men and 23% of women). Multivariable adjusted prevalence ratio [PR (95% CI)] for DM were: 1.00 (ref), 1.14 (0.90-1.44), 1.33 (1.04-1.70), 1.33 (1.06-1.68), 1.26 (0.99-1.61), and 1.52 (1.17-1.97) for egg consumption of <1/month, 1-3/month, 1/week, 2/week, 3-4/week, and 5+/week, respectively, p for linear trend 0.0024. Corresponding multivariable adjusted hazard ratios were 1.00 (ref), 0.88 (0.65-1.19), 0.94 (0.68-1.30), 0.91 (0.66-1.25), 1.11 (0.81-1.52), and 1.17 (0.81-1.70), respectively, during a mean follow up of 7.3 years (p for linear trend 0.22).
While egg consumption was positively associated with prevalent DM, prospective analysis did not show an association of egg intake with incidence of DM among African Americans.
2型糖尿病(DM)对非裔美国人的影响尤为严重。关于鸡蛋摄入量与糖尿病风险之间关联的数据较为稀少。我们旨在研究鸡蛋摄入量与非裔美国人糖尿病患病率及发病率之间是否存在关联。
我们分析了杰克逊心脏研究中4568名参与者的基线数据。通过专门为此人群设计的食物频率问卷获取鸡蛋摄入量信息。我们使用广义估计方程计算糖尿病的校正患病率比,并使用Cox回归估计糖尿病的风险比及相应的95%置信区间(CI)。
平均年龄为55±13岁,64%的受试者为女性。男性鸡蛋摄入频率中位数为每周2次,女性为每周1次。总体糖尿病患病率为22%(男性为21%,女性为23%)。糖尿病的多变量校正患病率比[PR(95%CI)]分别为:每月<1次时为1.00(参照),1 - 3次/月时为1.14(0.90 - 1.44),每周1次时为1.33(1.04 - 1.70),每周2次时为1.33(1.06 - 1.68),每周3 - 4次时为1.26(0.99 - 1.61),每周5次及以上时为1.52(1.17 - 1.