Struijk Dirk G
Dianet Foundation, Amsterdam, Utrecht , The Netherlands.
NDT Plus. 2008 Oct;1(Suppl 4):iv29-iv35. doi: 10.1093/ndtplus/sfn121.
Background. Indirect methods can be used to provide valuable information about peritoneal structure and function for the indirect analysis of peritoneal membrane. Methods. The focus of this paper will be on the commonly available tools for this purpose. First, the value and clinical relevance of CA125 as a marker of mesothelial cell mass in peritoneal effluent will be evaluated. Thereafter, monitoring the peritoneal membrane by using its properties to transport solutes and water will be discussed. Results. The data obtained can be useful for tailoring dialysis adequacy, analysis of clinical problems such as ultrafiltration failure or to predict the development of peritoneal sclerosis.
背景。间接方法可用于提供有关腹膜结构和功能的有价值信息,以对腹膜进行间接分析。方法。本文重点将放在为此目的常用的工具上。首先,将评估CA125作为腹膜透析液中间皮细胞量标志物的价值和临床相关性。此后,将讨论利用腹膜转运溶质和水的特性来监测腹膜。结果。所获得的数据可有助于调整透析充分性、分析诸如超滤失败等临床问题或预测腹膜硬化的发展。