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中国北京怀柔水库和官厅水库食用鱼体内有机氯农药(OCPs)和多氯联苯(PCBs)的人体健康风险。

Human health risk of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in edible fish from Huairou Reservoir and Gaobeidian Lake in Beijing, China.

机构信息

Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China; Graduate School of the Chinese Academy of Sciences, Beijing 100039, China.

Beijing Municipal Drainage Corporation, Beijing 100022, China.

出版信息

Food Chem. 2008 Jul 15;109(2):348-54. doi: 10.1016/j.foodchem.2007.12.047. Epub 2007 Dec 25.

Abstract

Organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were measured by a gas chromatography-mass spectometry (GC-MS) in some edible fish from Huairou Reservoir and Gaobeidian Lake in Beijing, China. The concentrations of OCPs and PCBs were higher in fish (except Misgurnus anguillicaudatus) from Gaobeidian Lake than in those from Huairou Reservoir. The average concentrations of HCHs, DDTs and PCBs in fish ranged from 0.58 to 8.48, 7.54 to 88.3, below limit of detection (nd) to 22.7ng/g wet weight, respectively. β-HCH, p,p'-DDE and PCB153 were the most abundant compounds among HCHs, DDTs and PCBs, respectively. Risk assessments of OCPs and PCBs for humans were estimated according to three different guidelines. The results indicated that fish intake would not pose a health risk to humans with a consumption of 7.4±8.6g/person day according to the acceptable daily intake (ADI) and minimal risk level (MRL) in the two environments. However, the hazardous ratio of the 95th percentile for PCBs in fish from Gaobeidian Lake exceeded 1, which suggested that daily exposure to PCBs had a lifetime cancer risk of greater than 1 in 1,000,000.

摘要

在中国北京的怀柔水库和高碑店湖,采用气相色谱-质谱法(GC-MS)对一些食用鱼体中的有机氯农药(OCPs)和多氯联苯(PCBs)进行了测量。高碑店湖鱼体中的 OCPs 和 PCBs 浓度高于怀柔水库。鱼体中 HCHs、DDTs 和 PCBs 的平均浓度范围分别为 0.58-8.48、7.54-88.3 和低于检测限(nd)至 22.7ng/g 湿重。β-HCH、p,p'-DDE 和 PCB153 是 HCHs、DDTs 和 PCBs 中最丰富的化合物。根据三种不同的准则,对 OCPs 和 PCBs 对人体的风险进行了评估。结果表明,根据可接受日摄入量(ADI)和两个环境中的最小风险水平(MRL),鱼类的摄入量对于人类健康不会构成风险,摄入量为 7.4±8.6g/人/天。然而,高碑店湖鱼体中 PCBs 的 95%百分位危险比超过了 1,这表明每天接触 PCBs 会使终生患癌症的风险超过 1/100 万。

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