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机器人甲状腺切除术与传统开放性甲状腺切除术治疗分化型甲状腺癌的Meta分析

Robotic thyroidectomy versus conventional open thyroidectomy for differentiated thyroid cancer: meta-analysis.

作者信息

Wang Y-C, Liu K, Xiong J-J, Zhu J-Q

机构信息

Department of Thyroid and Breast Surgery,West China Hospital,Sichuan University,Chengdu,China.

Department of Cardiology,West China Hospital,Sichuan University,Chengdu,China.

出版信息

J Laryngol Otol. 2015 Jun;129(6):558-67. doi: 10.1017/S002221511500122X. Epub 2015 May 25.

Abstract

OBJECTIVE

To conduct a meta-analysis to compare the short-term outcomes of robotic thyroidectomy and conventional open thyroidectomy for differentiated thyroid cancer.

METHODS

Medline, Embase, Science Citation Index Expanded and the Cochrane Library databases were searched for relevant literature. The evaluated endpoints were intra-operative and post-operative outcomes.

RESULTS

Twelve eligible, non-randomised comparative studies involving 2513 patients were included, with 923 patients in the robotic thyroidectomy group and 1590 patients in the conventional open thyroidectomy group. Meta-analysis results revealed that robotic thyroidectomy was associated with significantly longer operative time and a lower number of retrieved central lymph nodes, as compared with conventional open thyroidectomy. No significant differences were found between robotic thyroidectomy and conventional open thyroidectomy in terms of post-operative outcomes.

CONCLUSION

Robotic thyroidectomy appears to be a feasible and safe surgical procedure for patients with differentiated thyroid cancer. However, more high-quality randomised clinical trials should be undertaken to confirm these findings.

摘要

目的

进行一项荟萃分析,以比较机器人甲状腺切除术和传统开放性甲状腺切除术治疗分化型甲状腺癌的短期疗效。

方法

检索Medline、Embase、科学引文索引扩展版和Cochrane图书馆数据库中的相关文献。评估的终点为术中及术后结果。

结果

纳入了12项符合条件的非随机对照研究,共涉及2513例患者,其中机器人甲状腺切除术组923例,传统开放性甲状腺切除术组1590例。荟萃分析结果显示,与传统开放性甲状腺切除术相比,机器人甲状腺切除术的手术时间显著更长,中央区淋巴结清扫数目更少。机器人甲状腺切除术和传统开放性甲状腺切除术在术后结果方面未发现显著差异。

结论

对于分化型甲状腺癌患者,机器人甲状腺切除术似乎是一种可行且安全的手术方法。然而,需要开展更多高质量的随机临床试验来证实这些发现。

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