Jia Zhen-Yi, Yang Jun, Tong Da-Nian, Peng Jia-Yuan, Zhang Zhong-Wei, Liu Wei-Jie, Xia Yang, Qin Huan-long
1 Department of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Int Surg. 2015 May;100(5):841-8. doi: 10.9738/INTSURG-D-14-00245.1.
To determine the prevalence of nutritional risk in surgical departments and to evaluate the impact of nutritional support on clinical outcomes. The nutritional risk in different surgical diseases and the different way of nutritional support on clinical outcomes in patients at nutritional risk remain unclear. Hospitalized patients from general surgical departments were screened using the Nutritional Risk Screening (NRS) 2002 questionnaire on admission. Data were collected on nutritional risk, complications, and length of stay (LOS). Overall, 5034 patients were recruited; the overall prevalence of nutritional risk on admission were 19.2%. The highest prevalence was found among patients with gastric cancer. At-risk patients had more complications and longer LOS than nonrisk patients. Of the at-risk patients, the complication rate was significantly lower and LOS was significantly shorter in the nutritional-support group than in the no-support group (20.9 versus 30.0%, P < 0.05). Subgroup analysis showed reduced complication rates and LOS only in patients with gastric cancer, colorectal cancer, and hepato-pancreato-biliary (HPB) cancer. Significantly lower complication rates relative to nonsupported patients were found among patients who received enteral nutrition or who received support for 5 to 7 days, or daily support entailing 16 to 25 kcal/kg of nonprotein energy. Different surgical diseases have different levels of nutritional risk. The provision of nutritional support was associated with a lower complication rate and a shorter LOS for gastric, colorectal, and HPB cancer patients at nutritional risk. The improper use of nutritional support may not improve outcomes for at-risk patients.
确定外科各科室营养风险的患病率,并评估营养支持对临床结局的影响。不同外科疾病中的营养风险以及营养支持方式对存在营养风险患者临床结局的影响仍不明确。对普通外科住院患者入院时使用营养风险筛查(NRS)2002问卷进行筛查。收集有关营养风险、并发症和住院时间(LOS)的数据。总体而言,共招募了5034例患者;入院时营养风险的总体患病率为19.2%。胃癌患者中患病率最高。有风险的患者比无风险的患者有更多并发症且住院时间更长。在有风险的患者中,营养支持组的并发症发生率明显低于无支持组,住院时间也明显更短(20.9%对30.0%,P<0.05)。亚组分析显示,仅在胃癌、结直肠癌和肝胰胆(HPB)癌患者中并发症发生率和住院时间有所降低。在接受肠内营养、接受5至7天支持或每日支持提供16至25 kcal/kg非蛋白能量的患者中,相对于未接受支持的患者,并发症发生率明显更低。不同的外科疾病有不同程度的营养风险。对于存在营养风险的胃癌、结直肠癌和HPB癌患者,提供营养支持与较低的并发症发生率和较短的住院时间相关。营养支持使用不当可能无法改善有风险患者的结局。