Hruban Lukáš, Spilka Jiří, Chudáček Václav, Janků Petr, Huptych Michal, Burša Miroslav, Hudec Adam, Kacerovský Marian, Koucký Michal, Procházka Martin, Korečko Vladimír, Seget'a Jan, Šimetka Ondřej, Měchurová Alena, Lhotská Lenka
Department of Gynecology and Obstetrics, Masaryk University Hospital, Brno, Czech Republic.
Department of Cybernetics, Faculty of Electrical Engineering, Czech Technical University in Prague, Prague, Czech Republic.
J Eval Clin Pract. 2015 Aug;21(4):694-702. doi: 10.1111/jep.12368. Epub 2015 May 26.
RATIONALE, AIMS AND OBJECTIVES: To evaluate obstetricians' inter- and intra-observer agreement on intrapartum cardiotocogram (CTG) recordings and to examine obstetricians' evaluations with respect to umbilical artery pH and base deficit.
Nine experienced obstetricians annotated 634 intrapartum CTG recordings. The evaluation of each recording was divided into four steps: evaluation of two 30-minute windows in the first stage of labour, evaluation of one window in the second stage of labour and labour outcome prediction. The complete set of evaluations used for this experiment is available online. The inter- and intra-observer agreement was evaluated using proportion of agreement and kappa coefficient. Clinicians' sensitivity and specificity was computed with respect to umbilical artery pH, base deficit and to Apgar score at the fifth minute.
The overall proportion of agreement between clinicians reached 48% with 95% confidence intervals (CI) (CI: 47-50). Regarding the different classes, proportion of agreement ranged from 57% (CI: 54-60) for normal to 41% (CI: 36-46) for pathological class. The sensitivity of clinicians' majority vote to objective outcome was 39% (CI: 16-63) for the umbilical artery base deficit and 27% (CI: 16-42) for pH. The specificity was 89% (CI: 86-92) for both types of objective outcome.
The reported inter-/intra-observer variability is large and this holds irrespective of clinicians' experience or work place. The results support the need of modernized guidelines for CTG evaluation and/or objectivization and repeatability by introduction of a computerized approach that could standardize the process of CTG evaluation within the delivery ward.
原理、目的和目标:评估产科医生在产时胎心监护(CTG)记录方面的观察者间和观察者内一致性,并检查产科医生关于脐动脉pH值和碱缺失的评估情况。
九名经验丰富的产科医生对634份产时CTG记录进行标注。每份记录的评估分为四个步骤:第一产程中两个30分钟时段的评估、第二产程中一个时段的评估以及分娩结局预测。本实验所用的完整评估集可在线获取。使用一致性比例和kappa系数评估观察者间和观察者内的一致性。计算临床医生相对于脐动脉pH值、碱缺失以及出生后第5分钟阿氏评分的敏感性和特异性。
临床医生之间的总体一致性比例达到48%,95%置信区间(CI)为(CI:47 - 50)。对于不同类别,一致性比例从正常类别的57%(CI:54 - 60)到病理类别的41%(CI:36 - 46)不等。临床医生多数投票对客观结局的敏感性,对于脐动脉碱缺失为39%(CI:16 - 63),对于pH值为27%(CI:16 - 42)。对于两种客观结局类型,特异性均为89%(CI:86 - 92)。
报告的观察者间/内变异性很大,且与临床医生的经验或工作地点无关。结果支持需要通过引入计算机化方法来实现CTG评估指南的现代化和/或客观化及可重复性,从而使产房内CTG评估过程标准化。