Youssef Marwan, Neufang Achim, Jungmann Florian, Vahl Christian-Friedrich, Dorweiler Bernhard
Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, University Medical Center, Johannes-Gutenberg University, Mainz, Germany.
Department of Radiology, University Medical Center, Johannes-Gutenberg University, Mainz, Germany.
J Vasc Surg. 2015 Sep;62(3):594-9. doi: 10.1016/j.jvs.2015.04.386. Epub 2015 Jun 6.
In thoracoabdominal aortic aneurysms (TAAAs), a paradigm shift is observed from open surgery toward total endovascular aortic repair using fenestrated and branched endografts. Whereas outcome after open replacement in terms of mortality and paraplegia has been evaluated extensively, no studies exist addressing long-term patency of visceral and renal vessels. To enable comparison of target vessel patency between open and endovascular treatment, we analyzed our series of open TAAA replacements.
Our vascular surgery database was screened for patients who received open TAAA replacement between 1998 and 2012, and patient records were analyzed retrospectively. All available imaging scans (computed tomography and magnetic resonance angiography: preoperative, postoperative, and follow-up) were evaluated for graft and vessel patency.
We identified 62 patients (mean age, 66 ± 10 years; 40 men) who had been operated on for aneurysms of Crawford types I (8), II (13), III (13), and IV (24) and Safi type V (4). A total of 181 vessels were revascularized by either patch inclusion (n = 147) or selective revascularization (bypass or transposition, n = 34); 48 survived the procedure, resulting in a number of vessels available for follow-up of 154 (patch, 126; selective revascularization, 28). The respective patency rates for overall, patch, and selective revascularization were 95.2%, 94.2%, and 100% at 5 years and 83.7%, 81.3%, and 100% at 10 years, respectively. In addition, a trend for better performance of selective revascularization (bypass or transposition) was evident as all vessel occlusions were observed in cases of patch inclusion, whereas all selectively revascularized vessels were patent. The respective patency rates for the celiac trunk, superior mesenteric artery, and left and right renal artery were 100%, 97.5%, 92.3%, and 90.3% at 5 years.
In our series of open thoracoabdominal aortic replacement, excellent patency rates for revascularized renal and visceral vessels were observed during long-term follow-up. We were able to provide a reference value of long-term target vessel patency that can and should be taken into account to judge the efficacy of endovascular repair in TAAA.
在胸腹主动脉瘤(TAAA)治疗中,正经历从开放手术向使用开窗和分支型腔内移植物进行全腔内主动脉修复的模式转变。尽管开放置换术后在死亡率和截瘫方面的结局已得到广泛评估,但尚无研究涉及内脏和肾血管的长期通畅情况。为了能够比较开放手术和腔内治疗中靶血管的通畅情况,我们分析了我们一系列开放TAAA置换病例。
在我们的血管外科数据库中筛选1998年至2012年间接受开放TAAA置换的患者,并对患者记录进行回顾性分析。对所有可用的影像学扫描(计算机断层扫描和磁共振血管造影:术前、术后及随访)评估移植物和血管的通畅情况。
我们确定了62例患者(平均年龄66±10岁;40例男性),他们接受了Crawford I型(8例)、II型(13例)、III型(13例)和IV型(24例)以及Safi V型(4例)动脉瘤的手术。共有181支血管通过补片植入(n = 147)或选择性血运重建(旁路或转位,n = 34)实现血运重建;48例患者术后存活,从而有154支血管可供随访(补片植入血管126支;选择性血运重建血管28支)。总体、补片植入和选择性血运重建的5年通畅率分别为95.2%、94.2%和100%,10年通畅率分别为83.7%、81.3%和100%。此外,选择性血运重建(旁路或转位)表现更佳的趋势明显,因为所有血管闭塞均见于补片植入病例,而所有选择性血运重建的血管均保持通畅。腹腔干、肠系膜上动脉以及左、右肾动脉的5年通畅率分别为100%、97.5%、92.3%和90.3%。
在我们这一系列开放胸腹主动脉置换病例中,长期随访期间观察到血运重建的肾血管和内脏血管通畅率极佳。我们能够提供长期靶血管通畅的参考值,在判断TAAA腔内修复的疗效时可以且应该考虑这一参考值。