甲状腺病变的定量剪切波弹性成像与病理结构之间的相关性
Correlation between quantitative shear wave elastography and pathologic structures of thyroid lesions.
作者信息
Fukuhara Takahiro, Matsuda Eriko, Endo Yukari, Takenobu Masao, Izawa Shoichiro, Fujiwara Kazunori, Kitano Hiroya
机构信息
Department of Otolaryngology-Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan.
Department of Otolaryngology-Head and Neck Surgery, Tottori University Faculty of Medicine, Yonago, Japan.
出版信息
Ultrasound Med Biol. 2015 Sep;41(9):2326-32. doi: 10.1016/j.ultrasmedbio.2015.05.001. Epub 2015 Jun 6.
The aim of this study was to determine the correlation between shear wave velocity (SWV) generated by acoustic radiation force impulse and the pathologic structure of thyroid lesions. A total of 599 thyroid tissue samples were divided into four groups based on pathologic structure: 254 normal thyroid tissue samples as a control, 128 with chronic autoimmune thyroiditis (CAT) that demonstrated diffuse fibrosis, 165 with benign nodules that had high cell density and 52 with papillary thyroid carcinoma (PTC) that showed high cell density and fibrosis. The mean SWVs in each group were as follows: 1.60 ± 0.18 m/s in normal thyroid, 2.55 ± 0.28 m/s in CAT, 1.72 ± 0.31 m/s in benign nodules and 2.66 ± 0.95 m/s in PTC. The SWVs of CAT and PTC were significantly higher than those of normal thyroid, (p < 0.001). SWV was significantly affected by fibrosis.
本研究的目的是确定声辐射力脉冲产生的剪切波速度（SWV）与甲状腺病变病理结构之间的相关性。根据病理结构，共599个甲状腺组织样本被分为四组：254个正常甲状腺组织样本作为对照，128个患有表现为弥漫性纤维化的慢性自身免疫性甲状腺炎（CAT），165个具有高细胞密度的良性结节，以及52个具有高细胞密度和纤维化的甲状腺乳头状癌（PTC）。每组的平均SWV如下：正常甲状腺为1.60±0.18 m/s，CAT为2.55±0.28 m/s，良性结节为1.72±0.31 m/s，PTC为2.66±0.95 m/s。CAT和PTC的SWV显著高于正常甲状腺（p<0.001）。SWV受纤维化的显著影响。
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