Khashab Tamer, Sehgal Lalit, Medeiros L Jeffrey, Samaniego Felipe
Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
BMJ Case Rep. 2015 Jun 12;2015:bcr2014209014. doi: 10.1136/bcr-2014-209014.
Interdigitating dendritic cell sarcoma (IDCS) is a rare tumour; only seven cases of IDCS associated with chronic lymphocytic leucaemia/small lymphocytic lymphoma (CLL/SLL) have been reported. We present the case of a 60-year-old man who presented with fevers, night sweats and significant unintentional weight loss. Investigations led to a diagnosis of synchronous SLL and IDCS. Subsequent fluorodeoxyglucose (FDG) positron emission tomography CT (PET-CT) imaging revealed an unusual clinical course with spontaneously resolving highly metabolic lesions. After 42 months of follow-up, the patient remains free of clinical symptoms and evidence of IDCS.
交错突细胞肉瘤(IDCS)是一种罕见肿瘤;仅有7例IDCS与慢性淋巴细胞白血病/小淋巴细胞淋巴瘤(CLL/SLL)相关的病例报道。我们报告一例60岁男性患者,其表现为发热、盗汗及明显的非故意体重减轻。检查诊断为同步性SLL和IDCS。随后的氟脱氧葡萄糖(FDG)正电子发射断层扫描CT(PET-CT)成像显示了一个不寻常的临床过程,即高代谢病灶自发消退。经过42个月的随访,患者仍无临床症状及IDCS证据。