Kanık Esra Toprak, Yılmaz Özge, Türkeli Ahmet, Şahin Şebnem, Yüksel Hasan
Division of Pediatric Allergy and Pulmonology Unit, Celal Bayar University Faculty of Medicine, Manisa, Turkey.
Department of Pediatrics, Celal Bayar University Faculty of Medicine, Manisa, Turkey.
Turk Pediatri Ars. 2014 Dec 1;49(4):344-7. doi: 10.5152/tpa.2014.306. eCollection 2014 Dec.
Follicular bronchiolitis (FB) is a benign progressive lung disease. It is characterized with lymphoplasmocellular infiltration and hyperplastic follicles in the peribronchial areas in the small airways. Follicular bronchiolitis should be considered in cases where chronic cough, recurrent upper respiratory tract infections and progressive dyspnea are observed in children. The diagnosis should be supported by lung biopsy. A 8-year old female patient presented to our hospital with complaints including continuing cough and wheezing. Bilateral extensive rales and rhonchi in the lungs were heard on auscultation and lung graphy revealed reticuloglandular appearance. Bilateral extensive septal thickennings, reticulonodular appearance, patchy bronchiectasis, bronchiolectasis and peribronchial thickennings were found on high-resolution thoracal computarized tomography. A diagnosis of follicular bronchiolitis was made as a result of lung biopsy. Improvement was observed in the complaints and findings of our patient after methylprednisolone treatment. This patient was presented to emphasize rare interstitial lung diseases should also be considered in children who present with a clinical picture of chronic bronchial obstruction and do not respond to standard treatment.
滤泡性细支气管炎(FB)是一种良性进行性肺部疾病。其特征为小气道支气管周围区域出现淋巴浆细胞浸润和滤泡增生。在儿童出现慢性咳嗽、反复上呼吸道感染和进行性呼吸困难的情况下,应考虑滤泡性细支气管炎。诊断应通过肺活检来支持。一名8岁女性患者因持续咳嗽和喘息等症状前来我院就诊。听诊时双肺可闻及广泛啰音和哮鸣音,肺部影像学检查显示网状结节状表现。高分辨率胸部计算机断层扫描发现双侧广泛的间隔增厚、网状结节状表现、斑片状支气管扩张、细支气管扩张和支气管周围增厚。经肺活检诊断为滤泡性细支气管炎。甲基强的松龙治疗后,患者的症状和检查结果有所改善。介绍该病例是为了强调,对于呈现慢性支气管阻塞临床表现且对标准治疗无反应的儿童,也应考虑罕见的间质性肺疾病。