Hadley W K
San Francisco General Hospital, CA 94110.
Am J Hosp Pharm. 1989 Dec;46(12 Suppl 3):S4-7.
Transmission of the human immunodeficiency virus (HIV) and other blood-borne viruses in hospitals is discussed, and the infection control system and worker protection and education plan at San Francisco General Hospital (SFGH) are described. The acquired immunodeficiency syndrome (AIDS) epidemic has led to increased concern about occupationally acquired infections in health-care workers. As the number of HIV-infected persons increases, so does the risk of infection. Occupationally acquired HIV infection of health-care workers occurs principally in nurses, phlebotomists, and laboratory technicians through accidental subcutaneous injection of contaminated blood; splashing of blood onto open skin lesions, the eyes, and mucous membranes represents another route of exposure. The risk of infection from a single needle-stick exposure to HIV-infected blood is about 0.4%. Other blood-borne viruses to which employees are vulnerable include hepatitis B virus and human T-cell lymphotropic viruses, which may cause leukemia and lymphoma. SFGH has a comprehensive infection control system. Specimen containers are enclosed in transparent secondary containers, the worker is encouraged to wear protective clothing when necessary, and specific needle-stick precautions are promoted. There is also a health-care worker protection and education plan. The employee health services department provides immunizations, keeps records on accidental exposures, and operates a hot line. The education committee disseminates educational materials and arranges lectures. Infection control and education provide simple but effective measures for protecting hospital employees against HIV and other occupationally acquired infections.
本文讨论了医院中人类免疫缺陷病毒(HIV)及其他血源性病原体的传播情况,并介绍了旧金山总医院(SFGH)的感染控制系统以及工作人员保护与教育计划。获得性免疫缺陷综合征(AIDS)的流行使得人们越来越关注医护人员的职业感染问题。随着HIV感染者数量的增加,感染风险也随之上升。医护人员职业性感染HIV主要发生在护士、采血员和实验室技术人员身上,通常是由于意外皮下注射受污染血液所致;血液溅到开放性皮肤损伤处、眼睛和黏膜上是另一种暴露途径。单次针刺暴露于HIV感染血液的感染风险约为0.4%。员工易感染的其他血源性病原体包括乙型肝炎病毒和人类嗜T细胞病毒,后者可能导致白血病和淋巴瘤。SFGH拥有一套全面的感染控制系统。标本容器置于透明的二级容器中,必要时鼓励工作人员穿防护服,并推广特定的针刺预防措施。此外,还有一项医护人员保护与教育计划。员工健康服务部门提供免疫接种、记录意外暴露情况并开通热线。教育委员会分发教育材料并安排讲座。感染控制与教育为保护医院员工免受HIV及其他职业性感染提供了简单而有效的措施。