Tracey M L, McHugh S M, Buckley C M, Canavan R J, Fitzgerald A P, Kearney P M
Department of Epidemiology and Public Health, University College, Cork, Republic of Ireland.
Department of Public Health, Heath Service Executive (HSE) South, Cork, Republic of Ireland.
Diabet Med. 2016 Apr;33(4):441-5. doi: 10.1111/dme.12845. Epub 2015 Aug 16.
To investigate the prevalence of diagnosed Type 2 diabetes and its related complications in a nationally representative sample of older adults in the Republic of Ireland.
Cross-sectional analysis of a population-based sample of adults aged ≥ 50 years from the first wave of The Irish Longitudinal Study on Ageing (TILDA), (2009-2011). Diagnosed Type 2 diabetes prevalence was estimated by self-report or the use of oral hypoglycaemic agents. The prevalence of microvascular and macrovascular complications was determined by self-report.
Diagnosed Type 2 diabetes prevalence was 8.4% [95% confidence interval (CI): 7.8-9.0%] and was higher among men [10.3% (95% CI: 9.4-11.2%)] than women [6.6% (95% CI: 5.9-7.5%)]; P ≤ 0.001. Among participants with diagnosed Type 2 diabetes, the overall prevalence of microvascular complications was 26.0% (95% CI: 22.4-30.0%) with no evidence of gender-specific differences (P = 0.7). The overall prevalence of macrovascular complications was 15.1% (95% CI: 12.2-18.4%) and was higher among men [17.8% (95% CI: 14.3-23.1%)] than women [11.4% (95% CI: 7.7-16.4%)]; P ≤ 0.001.
In the absence of a national diabetes register, these findings provide a robust estimate of the national prevalence of diagnosed Type 2 diabetes and level of complications among adults aged 50 years and over in Ireland.
调查爱尔兰共和国具有全国代表性的老年人群样本中已诊断的2型糖尿病及其相关并发症的患病率。
对爱尔兰老龄化纵向研究(TILDA)第一波(2009 - 2011年)中年龄≥50岁的成年人群样本进行横断面分析。已诊断的2型糖尿病患病率通过自我报告或使用口服降糖药来估计。微血管和大血管并发症的患病率通过自我报告确定。
已诊断的2型糖尿病患病率为8.4%[95%置信区间(CI):7.8 - 9.0%],男性患病率[10.3%(95%CI:9.4 - 11.2%)]高于女性[6.6%(95%CI:5.9 - 7.5%)];P≤0.001。在已诊断为2型糖尿病的参与者中,微血管并发症的总体患病率为26.0%(95%CI:22.4 - 30.0%),没有证据表明存在性别差异(P = 0.7)。大血管并发症的总体患病率为15.1%(95%CI:12.2 - 18.4%),男性患病率[17.8%(95%CI:14.3 - 23.1%)]高于女性[11.4%(95%CI:7.7 - 16.4%)];P≤0.001。
在没有国家糖尿病登记册的情况下,这些发现为爱尔兰50岁及以上成年人中已诊断的2型糖尿病的全国患病率和并发症水平提供了可靠估计。