Bredahl Kim, Jensen Leif Panduro, Schroeder Torben V, Sillesen Henrik, Nielsen Henrik, Eiberg Jonas P
Department of Vascular Surgery, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
Department of Vascular Surgery, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark; The Danish Vascular Registry, Rigshospitalet, Copenhagen, Denmark.
J Vasc Surg. 2015 Jul;62(1):75-82. doi: 10.1016/j.jvs.2015.02.025.
Open surgery has given way to endovascular grafting in patients with aortoiliac occlusive disease. The growing use of endovascular grafts means that fewer patients with aortoiliac occlusive disease have open surgery. The declining open surgery caseload challenges the surgeon's operative skills, particularly because open surgery is increasingly used in those patients who are unsuitable for endovascular repair and hence technically more demanding. We assessed the early outcome after aortic bifurcated bypass procedures during two decades of growing endovascular activity and identified preoperative risk factors.
Data on patients with chronic limb ischemia were prospectively collected during a 20-year period (1993 to 2012). The data were obtained from the Danish Vascular Registry, assessed, and merged with data from The Danish Civil Registration System.
We identified 3623 aortobifemoral and 144 aortobiiliac bypass procedures. The annual caseload fell from 323 to 106 during the study period, but the 30-day mortality at 3.6% (95% confidence interval [CI], 3.0-4.1) and the 30-day major complication rate remained constant at 20% (95% CI, 18-21). Gangrene (odds ratio [OR], 3.3; 95% CI, 1.7-6.5; P = .005) was the most significant risk factor for 30-day mortality, followed by renal insufficiency (OR, 2.5; 95% CI, 1.1-5.8; P = .035) and cardiac disease (OR, 2.1; 95% CI, 1.4-3.1; P < .001). Multiorgan failure, mesenteric ischemia, need for dialysis, and cardiac complications were the most lethal complications, with mortality rates of 94%, 44%, 38%, and 34%, respectively.
Aortic bifurcated bypass is a high-risk procedure. Although open surgery has increasingly given way to endovascular repair, 30-day outcomes have remained stable during the past decade. Thus, it is still acceptable to consider an aortic bifurcated bypass whenever endovascular management is not feasible.
在主髂动脉闭塞性疾病患者中,开放手术已逐渐被血管腔内移植物植入术所取代。血管腔内移植物的使用日益增加,这意味着接受开放手术的主髂动脉闭塞性疾病患者越来越少。开放手术病例数量的减少对外科医生的手术技能构成了挑战,尤其是因为开放手术越来越多地用于那些不适合血管腔内修复且技术要求更高的患者。我们评估了在血管腔内治疗活动增加的二十年中,主动脉分叉旁路手术的早期结果,并确定了术前风险因素。
前瞻性收集了20年期间(1993年至2012年)慢性肢体缺血患者的数据。数据来自丹麦血管登记处,经过评估后与丹麦民事登记系统的数据合并。
我们确定了3623例主股动脉旁路手术和144例主髂动脉旁路手术。在研究期间,每年的病例数量从323例降至106例,但30天死亡率为3.6%(95%置信区间[CI],3.0 - 4.1),30天主要并发症发生率保持在20%(95%CI,18 - 21)不变。坏疽(比值比[OR],3.3;95%CI,1.7 - 6.5;P = 0.005)是30天死亡率最显著的风险因素,其次是肾功能不全(OR,2.5;95%CI,1.1 - 5.8;P = 0.035)和心脏病(OR,2.1;95%CI,1.4 - 3.1;P < 0.001)。多器官功能衰竭、肠系膜缺血、需要透析和心脏并发症是最致命的并发症,死亡率分别为94%、44%、38%和34%。
主动脉分叉旁路手术是一种高风险手术。尽管开放手术已越来越多地被血管腔内修复所取代,但在过去十年中30天的结果仍保持稳定。因此,当血管腔内治疗不可行时,考虑进行主动脉分叉旁路手术仍是可以接受的。