马拉维若（UK-427,857）的一种便捷合成方法：C-H官能化。
An expedient synthesis of maraviroc (UK-427,857) C-H functionalization.
作者信息
Bedell T Aaron, Hone Graham A B, Bois Justin Du, Sorensen Erik J
机构信息
Department of Chemistry, Princeton University, Princeton, NJ 08544, United States.
Department of Chemistry, Stanford University, Stanford, California 94305, United States.
出版信息
Tetrahedron Lett. 2015 Jun 3;56(23):3620-3623. doi: 10.1016/j.tetlet.2015.01.074.
Abstract
A new, concise synthesis of the CCR-5 receptor antagonist maraviroc (UK-427,857) from 3-phenyl-1-propanol has been completed in four steps featuring a site-selective C-H functionalization.
摘要
已通过以位点选择性C-H官能化为特色的四个步骤，完成了从3-苯基-1-丙醇出发对CCR-5受体拮抗剂马拉维若（UK-427,857）进行的全新简洁合成。
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