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深静脉血栓形成且有抗凝治疗短暂禁忌证患者可回收下腔静脉滤器的治疗结果

Outcomes of retrievable inferior vena cava filters in patients with deep vein thrombosis and transient contraindication for anticoagulation.

作者信息

Kim Hyung-Kee, Song Incheol, Jang Ji-Hoon, Oh Chang-Wug, Lee Jong-Min, Huh Seung

机构信息

Division of Vascular Surgery, Department of Surgery, Kyungpook National University School of Medicine, Daegu, Korea.

Department of Orthopedic Surgery, Kyungpook National University School of Medicine, Daegu, Korea.

出版信息

Ann Surg Treat Res. 2015 Jul;89(1):30-6. doi: 10.4174/astr.2015.89.1.30. Epub 2015 Jun 11.

Abstract

PURPOSE

To determine the efficacy of a retrievable inferior vena cava filter (IVCF) for patients with deep vein thrombosis (DVT) and transient contraindication for anticoagulant therapy, and to analyze the risk factors for filter thrombus in these patients.

METHODS

We retrospectively reviewed the records of 70 patients who received a retrievable IVCF from January 2007 to June 2014 because of documented DVT and transient contraindication for anticoagulant therapy. The protocol for follow-up care generally consisted of anticoagulant therapy after high-risk periods, follow-up CT around 2 weeks after IVCF placement, and retrieval if possible.

RESULTS

The 70 patients had a mean age of 61.8 years (range, 17-88 years), and 30 were male (43%). The indications for IVCF were recent trauma including surgery in 48 patients, recent hemorrhage in 14, and planned major surgery with DVT in 8 patients. Follow-up CT of 61 patients (87%) was performed. Aggravation or new development of pulmonary embolism (PE) was not found in any patient. Filter thrombus was detected in 23% of patients with follow-up CT (14/61). Filter thrombus was not detected in patients with isolated calf vein thrombosis (ICVT) (P = 0.079). The risk factor for filter thrombus was DVT progression on follow-up CT (P = 0.007) on multivariate analysis.

CONCLUSION

For patients with DVT and transient contraindication for anticoagulant therapy, a retrievable IVCF could prevent the aggravation or new development of PE. DVT progression on follow-up CT was associated with filter thrombus and ICVT was not related to filter thrombus in the present study.

摘要

目的

确定可回收下腔静脉滤器(IVCF)对深静脉血栓形成(DVT)且抗凝治疗存在短暂禁忌证患者的疗效,并分析这些患者发生滤器血栓的危险因素。

方法

我们回顾性分析了2007年1月至2014年6月期间因记录在案的DVT和抗凝治疗短暂禁忌证而接受可回收IVCF的70例患者的病历。随访方案通常包括高危期后的抗凝治疗、IVCF置入后约2周的随访CT检查,以及尽可能进行滤器取出。

结果

70例患者的平均年龄为61.8岁(范围17 - 88岁),男性30例(43%)。IVCF的置入指征包括近期外伤(包括手术)48例、近期出血14例、计划进行大手术合并DVT 8例。61例患者(87%)进行了随访CT检查。未发现任何患者出现肺栓塞(PE)加重或新发情况。在进行随访CT检查的患者中,23%(14/61)检测到滤器血栓。孤立性小腿静脉血栓形成(ICVT)患者未检测到滤器血栓(P = 0.079)。多因素分析显示,随访CT上DVT进展是滤器血栓形成的危险因素(P = 0.007)。

结论

对于DVT且抗凝治疗存在短暂禁忌证的患者,可回收IVCF可预防PE加重或新发。在本研究中,随访CT上DVT进展与滤器血栓相关,而ICVT与滤器血栓无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9e3/4481029/28d8642e5a50/astr-89-30-g001.jpg

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