煤炱菌黄变黑团壳产生嗜热杀酶菌素（久效霉素）。

Production of thermozymocidin (myriocin) by the pyrenomycete Melanconis flavovirens.

作者信息

Sasek V, Sailer M, Vokoun J, Musílek V

机构信息

Institute of Microbiology, Czechoslovak Academy of Sciences, Prague.

出版信息

J Basic Microbiol. 1989;29(6):383-90. doi: 10.1002/jobm.3620290619.

DOI:10.1002/jobm.3620290619

PMID:2614676

Abstract

Submerged culture of the pyrenomycete Melanconis flavovirens produces a strongly active antifungal antibiotic. The antibiotic was isolated from the culture mash. In purified compound the physico-chemical characteristics, including 1H NMR spectrum, were estimated. The antibiotic was found to be identical with thermozymocidin (myriocin) as confirmed by comparison with synthetically prepared thermozymocidin.

摘要

子囊菌黄变黑团壳菌的深层培养产生一种具有强烈活性的抗真菌抗生素。该抗生素从培养醪中分离得到。对纯化后的化合物进行了包括¹H NMR谱在内的物理化学特性评估。通过与合成制备的嗜热栖热放线菌素进行比较，发现该抗生素与嗜热栖热放线菌素（肉毒霉素）相同。