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非洲双相情感障碍的流行病学与负担:对来自非洲数据的系统评价

Epidemiology and burden of bipolar disorder in Africa: a systematic review of data from Africa.

作者信息

Esan Oluyomi, Esan Arinola

机构信息

Department of Psychiatry, University of Ibadan, Ibadan, Nigeria.

Department of Medicine, University College Hospital, Ibadan, Nigeria.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2016 Jan;51(1):93-100. doi: 10.1007/s00127-015-1091-5. Epub 2015 Jul 9.

Abstract

BACKGROUND

Bipolar disorder impacts negatively on the patient, the family, as well as the society. It taxes the health care services due to a combination of the illness with associated medical and psychiatric comorbidities. In Africa, unfortunately, knowledge of the epidemiology and burden of bipolar disorder is based mainly on studies from the USA and Europe. In this systematic review of literature from Africa, we highlight the epidemiology and burden of bipolar disorder.

METHODS

A systematic review of publications from Africa relating to the epidemiology and burden of bipolar disorder was conducted.

RESULT

Data from community surveys conducted in Nigeria and Ethiopia indicated a lifetime prevalence estimate of 0.1 % to 1.83 for bipolar disorder. Missed diagnosis rate of bipolar disorder was up to 36.2 %. In one study, 8.1 % of the males and 5.4 % of the females reported a previous suicide attempt. A study showed that up to 60 % of patients with bipolar disorder had at least one comorbidity. There were no reports on all-cause mortality and cost of illness.

CONCLUSION

Bipolar disorder is a major mental health problem in Africa. Scientific findings on bipolar disorder from Africa are consistent with the existing literature from other parts of the world. There still exists a dearth of high quality studies addressing the epidemiological, clinical, social, and economic burden of the disorder.

摘要

背景

双相情感障碍对患者本人、家庭乃至社会都会产生负面影响。由于该疾病与相关的医学及精神科合并症并存,给医疗服务带来了沉重负担。不幸的是,在非洲,关于双相情感障碍的流行病学及负担的认知主要基于来自美国和欧洲的研究。在本次对非洲文献的系统综述中,我们着重阐述双相情感障碍的流行病学及负担情况。

方法

对来自非洲的有关双相情感障碍流行病学及负担的出版物进行系统综述。

结果

在尼日利亚和埃塞俄比亚开展的社区调查数据显示,双相情感障碍的终生患病率估计为0.1%至1.83%。双相情感障碍的漏诊率高达36.2%。在一项研究中,8.1%的男性和5.4%的女性报告曾有过自杀未遂行为。一项研究表明,高达60%的双相情感障碍患者至少患有一种合并症。未发现关于全因死亡率和疾病成本的报告。

结论

双相情感障碍是非洲的一个主要心理健康问题。来自非洲的关于双相情感障碍的科学研究结果与世界其他地区的现有文献一致。目前仍缺乏高质量的研究来探讨该疾病的流行病学、临床、社会及经济负担。

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