Lee Heemoon, Cho Yang Hyun, Sung Kiick, Kim Wook Sung, Park Kay-Hyun, Park Pyo Won, Lee Young Tak
a Department of Thoracic and Cardiovascular Surgery , Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul , Korea.
b Department of Thoracic and Cardiovascular Surgery , Seoul National University Bundang Hospital, Seoul National University College of Medicine , Seoul , Korea.
Scand Cardiovasc J. 2015;49(6):331-6. doi: 10.3109/14017431.2015.1072236. Epub 2015 Aug 3.
The early and late outcomes of valve-sparing root replacement (VSR) in type A aortic dissection (AAD) are unknown. The aim of this study was to review the outcomes of VSR in AAD. We also compared the outcomes of VSR with the Bentall operation, which served as a standard reference technique.
We retrospectively reviewed 52 patients who underwent surgery for AAD and concomitant root replacement between 1998 and 2013 at Samsung Medical Center. Patients were divided into two groups: Bentall (n = 34) and VSR (n = 18). Two out of six surgeons performed VSR. The mean follow-up duration was 62.3 ± 46.5 months.
Preoperative characteristics were similar between the two groups except age (Bentall, 48 ± 11 years; VSR, 37 ± 11 years, p = 0.011). The aortic cross-clamping time was longer in the VSR group (Bentall, 185.8 ± 63.8; VSR, 241.4 ± 44.3 min, p = 0.002). There was no early death in the VSR group, but there was one in the Bentall group (p = 1.000). Despite the higher reoperation rate for aortic valve in the VSR group (Three reoperations) than in the Bentall group (no reoperation), major valve-related events and overall mortality did not differ between the two groups(p = 0.876 and 0.119, respectively). In multivariable analysis, the root replacement technique was not a risk factor for major valve-related events.
VSR seems to be equivalent to the Bentall procedure for AAD in terms of early and late outcomes. VSR can be considered as a viable option, particularly for young patients with favorable aortic valve leaflets undergoing surgery at an experienced center.
A型主动脉夹层(AAD)行保留瓣膜的主动脉根部置换术(VSR)的早期和晚期结果尚不清楚。本研究的目的是回顾AAD患者VSR的手术结果。我们还将VSR的结果与作为标准参考技术的Bentall手术的结果进行了比较。
我们回顾性分析了1998年至2013年在三星医疗中心接受AAD手术并同期行主动脉根部置换术的52例患者。患者分为两组:Bentall组(n = 34)和VSR组(n = 18)。6名外科医生中有2名进行VSR手术。平均随访时间为62.3±46.5个月。
除年龄外,两组术前特征相似(Bentall组,48±11岁;VSR组,37±11岁,p = 0.011)。VSR组主动脉阻断时间更长(Bentall组,185.8±63.8分钟;VSR组,241.4±44.3分钟,p = 0.002)。VSR组无早期死亡病例,而Bentall组有1例(p = 1.000)。尽管VSR组主动脉瓣再次手术率(3例再次手术)高于Bentall组(无再次手术),但两组主要瓣膜相关事件和总体死亡率无差异(分别为p = 0.876和0.119)。多变量分析显示,主动脉根部置换技术不是主要瓣膜相关事件的危险因素。
就早期和晚期结果而言,VSR似乎与Bentall手术治疗AAD效果相当。VSR可被视为一种可行的选择,特别是对于主动脉瓣叶良好的年轻患者,在经验丰富的中心进行手术。