溶组织内阿米巴新酶株的实验性产生支持了基因交换的假说。

Experimental production of new zymodemes of Entamoeba histolytica supports the hypothesis of genetic exchange.

作者信息

Blanc D, Nicholls R, Sargeaunt P G

机构信息

Department of Medical Protozoology, London School of Hygiene and Tropical Medicine, UK.

出版信息

Trans R Soc Trop Med Hyg. 1989 Nov-Dec;83(6):787-90. doi: 10.1016/0035-9203(89)90329-5.

DOI:10.1016/0035-9203(89)90329-5

PMID:2617647

Abstract

By mixing in culture zymodemes of Entamoeba histolytica, clones showing a different pattern from the 2 parents have been obtained on 3 occasions. Two new zymodemes (XI alpha- and XXI) have thus been produced, which belong to the third generation of a family of E. histolytica zymodemes apparently obtained by genetic exchange. A hypothesis for the molecular basis of those exchanges is discussed. We report also the observation of probable mutation.

摘要

通过在培养物中混合溶组织内阿米巴的酶谱型，已3次获得了与两个亲本表现出不同模式的克隆。由此产生了两种新的酶谱型（XIα型和XXI型），它们属于溶组织内阿米巴酶谱型家族的第三代，显然是通过基因交换获得的。文中讨论了这些交换的分子基础的假说。我们还报告了可能发生突变的观察结果。