Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Breast Cancer (Dove Med Press). 2015 Jul 7;7:173-8. doi: 10.2147/BCTT.S83725. eCollection 2015.
Although therapeutic mammoplasty (TM) was introduced for treatment of localized ductal carcinoma in situ and invasive breast carcinoma (stages I and II) in females with large breast size, the suitability of medial pedicle TM for treatment of breast tumors at different locations has not been established. The objective of this study was to assess the safety and esthetic outcome of medial pedicle TM for breast tumors at different locations.
The study was conducted from February 2012 to July 2014. Consecutive patients with early breast carcinoma with medium- and large-sized breasts, with or without ptosis, who were offered medial pedicle TM were included in the study. Patients who were not candidates for breast-conserving surgery or those with tumors located along the medial pedicle were excluded. All patients received immediate postoperative adjuvant chemoradiotherapy.
Thirty patients with a mean age of 48.5 years received medial pedicle TM in the breast harboring the tumor or, additionally, the other breast (N=14). The tumors were in the upper (60.0%), lower (26.7%), and lateral (13.3%) quadrants. Minor complications occurred in five cases (5/30, 16.7%) in the ipsilateral and in two (2/14, 14.3%) contralateral breasts. No wound dehiscence or areolar necrosis was recorded. A total of 22 (73.3%) patients were scored as excellent cosmesis. After a median follow-up of 20 months, no locoregional recurrence or distant metastases were observed.
TM using a medial pedicle is a safe and appealing technique among women with tumors at different locations.
尽管治疗性乳房成形术(TM)是为治疗乳房较大的女性的局限性导管原位癌和浸润性乳腺癌(I 期和 II 期)而引入的,但内侧蒂 TM 对不同部位乳房肿瘤的适用性尚未确定。本研究的目的是评估内侧蒂 TM 治疗不同部位乳房肿瘤的安全性和美容效果。
本研究于 2012 年 2 月至 2014 年 7 月进行。纳入了接受内侧蒂 TM 的中、大型乳房伴或不伴下垂的早期乳腺癌患者,且患者有保乳手术适应证,或肿瘤位于内侧蒂以外。所有患者均接受术后即刻辅助放化疗。
30 例年龄平均为 48.5 岁的患者接受了内侧蒂 TM 治疗,其中 14 例患者同时接受了对侧乳房的治疗。肿瘤位于乳房的上象限(60.0%)、下象限(26.7%)和外象限(13.3%)。同侧乳房发生 5 例(5/30,16.7%)和对侧乳房发生 2 例(2/14,14.3%)轻微并发症。未记录到伤口裂开或乳晕坏死。22 例(73.3%)患者的美容效果被评为优秀。中位随访 20 个月后,未观察到局部区域复发或远处转移。
对于不同部位肿瘤的女性,使用内侧蒂的 TM 是一种安全且吸引人的技术。