[冰片-水杨酸低共熔混合物的透皮吸收研究]
[Study on transdermal absorption of borneol-salicylic acid eutectic mixture].
作者信息
Cui D X, Sugibayashi K, Morimoto Y, Li F L
出版信息
Yao Xue Xue Bao. 1989;24(7):556-9.
PMID:2618699
Abstract
Borneol is an organic drug having property to form eutectic mixture with salicylic acid. We compared the transdermal absorption rate of borneol alone with that of borneol-salicylic acid eutectic mixture in hairless rats. The results showed that the borneol-salicylic acid eutectic mixture can evidently increase the absorption rate of borneol and provided a method for manufacturing borneol preparation which can easily be absorbed transdermally.
摘要
冰片是一种能与水杨酸形成低共熔混合物的有机药物。我们比较了冰片单独使用时与冰片 - 水杨酸低共熔混合物在无毛大鼠中的透皮吸收率。结果表明，冰片 - 水杨酸低共熔混合物能显著提高冰片的吸收率，并提供了一种制备易于经皮吸收的冰片制剂的方法。
相似文献
1
[Study on transdermal absorption of borneol-salicylic acid eutectic mixture].
Yao Xue Xue Bao. 1989;24(7):556-9.
2
[Study on rat nasal absorption in situ of borneol based on single pass perfusion method].
Zhongguo Zhong Yao Za Zhi. 2011 Sep;36(18):2489-92.
3
In situ and in vivo study of nasal absorption of borneol in rats.
Pharmazie. 2012 Oct;67(10):848-51.
4
[In vitro transdermal permeation of lidocaine-dodecanol binary eutectic system].
Yao Xue Xue Bao. 2005 Aug;40(8):764-8.
5
[The enhancing effect of borneol on the absorption of tetramethylpyrazine].
Yao Xue Xue Bao. 2009 Aug;44(8):915-21.
6
[Study on natural borneol and synthetic borneol affecting mucosal permeability of gardenia extract].
Zhongguo Zhong Yao Za Zhi. 2009 May;34(10):1207-10.
7
[Percutaneous penetration of mucopolysaccharide-polysulfate ester from a combination preparation].
Arzneimittelforschung. 1988 May;38(5):691-4.
8
[Effect of borneol/mentholum eutectic mixture on nasal-brain delivery of neurotoxin loaded nanoparticles].
Zhongguo Zhong Yao Za Zhi. 2009 Mar;34(6):698-701.
9
Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats.
J Asian Nat Prod Res. 2012;14(6):538-44. doi: 10.1080/10286020.2012.680439.
10
[Intestinal absorption properties of three components in salvianolic acid extract and the effect of borneol on their absorption in rats].
Yao Xue Xue Bao. 2010 Dec;45(12):1576-81.
Zotero 插件