[羽叶三七（Seem.）吴 & 冯变种叶中皂苷的研究]

[Studies on saponins from the leaves of Panax japonicus var. bipinnatifidus(Seem.)Wu et Feng].

作者信息

Wang D Q, Fan J, Feng B S, Li S R, Wang X B, Yang C R, Zhou J

出版信息

Yao Xue Xue Bao. 1989;24(8):593-9.

Abstract

Two new saponins, bipinnatifidusoside F1(XII) and F2(XIII), were isolated along with eleven known saponins from the dried leaves of Panax japonicus var.bipinnatifidus(Seem.)Wu et Feng collected in the Range of Qinling Mountains in China. By spectrometric analysis(FAB-MS,1H and 13CNMR,1H-1H COSY), their structures were elucidated as dammar-25(26)-ene-3 beta, 12 beta, 20(S),24 zeta-tetraol-(20-O-beta-D-glucopyranosyl)-3-O- beta-D-glucopyranosyl(1-2)-beta-D-glucopyranoside (bipinnatifidusodie F1) and dammar-22(23) ene-3 beta, 12 beta, 20(S),24 zeta-tetraol-(20-O-beta-D-glucopyranosyl)-3-O-beta- D-glucopyranosyl(1-2)-beta-D-glucopyranoside (bipinnatifidusoside F2), respectively. The known saponins were identified as ginsenoside F1,F2,F3,Rg2,Re,Rd,Rb1,Rb3, 24(S)-pseudoginsenoside F11, panasenoside and majoroside F1. Compared with bipinnatifidusoside F2, majoroside F3 was corrected as dammar-22(23)-ene-3 beta, 12 beta,20(S),24 zeta-tetraol-(20-O-beta-D- glucopyranosyl)-3-O-beta-D-glucopyranoside.

摘要

从采自中国秦岭山脉的羽叶三七（Panax japonicus var. bipinnatifidus (Seem.) Wu et Feng）干燥叶中，分离得到两个新皂苷，羽叶三七苷F1（XII）和F2（XIII），以及11个已知皂苷。通过光谱分析（FAB-MS、1H和13CNMR、1H-1H COSY），确定它们的结构分别为达玛-25(26)-烯-3β，12β，20(S)，24ζ-四醇-(20-O-β-D-吡喃葡萄糖基)-3-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖苷（羽叶三七苷F1）和达玛-22(23) -烯-3β，12β，20(S)，24ζ-四醇-(20-O-β-D-吡喃葡萄糖基)-3-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖苷（羽叶三七苷F2）。已知皂苷被鉴定为人参皂苷F1、F2、F3、Rg2、Re、Rd、Rb1、Rb3、24(S)-假人参皂苷F11、竹节人参皂苷和大三七苷F1。与羽叶三七苷F2相比，大三七苷F3被修正为达玛-22(23)-烯-3β，12β，20(S)，