年龄对尼日利亚哈科特港生育情况的影响
Effect of Age on Childbearing in Port Harcourt, Nigeria.
作者信息
Orazulike Ngozi C, Jeremiah Israel, Green Kinikanwo I, Uzoigwe Samuel A
机构信息
Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria;
Department of Obstetrics and Gynaecology, Niger Delta University, Wilberforce Island Bayelsa State, Nigeria.
出版信息
Int J Biomed Sci. 2015 Jun;11(2):82-5.
OBJECTIVES
To determine the effect of maternal age on pregnancy outcomes in women aged 40 years and above at the University of Port Harcourt Teaching Hospital.
METHODS
A retrospective comparative study was conducted on women aged ≥40 years (n=249) and a control group aged 20-29 years (n=249) who delivered at ≥28 weeks gestation between January 1, 2008 and December 31, 2012. The medical records of the patients were analyzed using Epi Info 6.04d. Association between maternal age and selected obstetrical variables were assessed using the chi-squared and the two-tailed Fisher exact test. Differences were considered statistically significant when p≤0.05.
RESULTS
The mean age of the women in the study group was 41.2 ±1.75 versus 26.10 ± 2.37 in the control group. Advanced maternal age was associated with a significantly higher rate of hypertensive disorders of pregnancy (p=0.01), diabetes mellitus (p<0.01), abnormal lies/presentation (p=0.04), caesarean deliveries (p<0.01) and low birth weight (p=0.04).
CONCLUSION
Older parturients have a higher risk of medical disorders of pregnancy. They are more likely to deliver by caesarean section and have low birth weight babies than their younger counterparts.
目的
确定哈科特港大学教学医院40岁及以上女性的产妇年龄对妊娠结局的影响。
方法
对2008年1月1日至2012年12月31日期间妊娠≥28周分娩的≥40岁女性（n = 249）和20 - 29岁对照组女性（n = 249）进行回顾性比较研究。使用Epi Info 6.04d分析患者的病历。采用卡方检验和双侧Fisher精确检验评估产妇年龄与选定产科变量之间的关联。当p≤0.05时，差异被认为具有统计学意义。
结果
研究组女性的平均年龄为41.2±1.75岁，而对照组为26.10±2.37岁。高龄产妇与妊娠高血压疾病（p = 0.01）、糖尿病（p < 0.01）、胎位异常/胎先露异常（p = 0.04）、剖宫产（p < 0.01）和低出生体重（p = 0.04）的发生率显著较高相关。
结论
高龄产妇发生妊娠相关疾病的风险较高。与年轻产妇相比，她们更有可能通过剖宫产分娩，且婴儿出生体重较低。
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