Department of Psychosomatic Medicine, University Medicine Rostock, Rostock, Germany.
German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
J Am Geriatr Soc. 2015 Aug;63(8):1527-33. doi: 10.1111/jgs.13561. Epub 2015 Jul 22.
To determine the association between hearing impairment and dementia.
Cross-sectional study.
Claims data of the Allgemeine Ortskrankenkasse, the largest public health insurance company in Germany.
Age-stratified sample of all insured persons aged 65 and above in the first quarter of 2007 (N = 1,338,462).
Metaregression analysis on the association between regional prevalence of dementia and hearing impairment controlled for major vascular risk factors, including hypertension, hypercholesterolemia, diabetes mellitus, and cerebrovascular disease. Dementia and hearing impairment diagnoses were defined according to International Classification of Diseases, Tenth Revision, codes. Ninety-five regions were distinguished according to the two-digit postal code of the place of residence.
A significant association was found between regional prevalences of dementia and hearing impairment that was preserved when controlling for major vascular risk factors (P = .003). Regional dementia prevalence increased by approximately 0.23% when the prevalence of hearing impairment increased by 1 standard deviation.
The relationship between hearing impairment and dementia has been repeatedly demonstrated on the individual level. The results of the current study confirm that this relationship also exists on a regional level. These findings underscore the potential role of hearing impairment as a risk factor for dementia that will be relevant for the management of elderly patients in general practice.
确定听力损伤与痴呆之间的关联。
横断面研究。
德国最大的公共健康保险公司 Allgemeine Ortskrankenkasse 的索赔数据。
2007 年第一季度所有年龄在 65 岁及以上的参保人员的年龄分层样本(N=1,338,462)。
在控制主要血管风险因素(包括高血压、高胆固醇血症、糖尿病和脑血管疾病)的情况下,对痴呆和听力损伤区域流行率之间的关联进行荟萃回归分析。痴呆和听力损伤的诊断是根据国际疾病分类,第十版代码定义的。根据居住地的两位数字邮政编码,区分了 95 个区域。
发现痴呆和听力损伤的区域流行率之间存在显著关联,在控制主要血管风险因素后仍然存在(P=0.003)。当听力损伤的流行率增加一个标准差时,区域痴呆的流行率增加了约 0.23%。
听力损伤与痴呆之间的关系在个体水平上已被反复证明。本研究的结果证实了这种关系在区域水平上也存在。这些发现强调了听力损伤作为痴呆的一个风险因素的潜在作用,这将与一般实践中老年患者的管理相关。