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Isolated ocular lichen planus in a child.

作者信息

Igras Estera, Kennedy Susan, MacDermott Emma Jane, Murphy Conor C

机构信息

Department of Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland.

Department of Ophthalmic Pathology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland.

出版信息

J AAPOS. 2015 Aug;19(4):381-3. doi: 10.1016/j.jaapos.2015.03.019. Epub 2015 Jul 23.

Abstract

Lichen planus (LP) is an autoimmune inflammatory condition of the skin and mucous membranes, of unknown aetiology, that infrequently involves the eye. Ocular LP has not been described in children. We present the case of an 8-year-old girl with severe, filamentous dry eyes and persistent conjunctival hyperemia with bilateral progressive conjunctival symblepharon. Her conjunctival biopsy showed heavy linear fibrinogen deposits along the basement membrane without IgG, IgA, IgM, or C3 deposition, consistent with LP. No skin or other mucosal lesions were present, suggesting a diagnosis of isolated conjunctival LP. Oral and topical cyclosporine combined with methotrexate and low-dose oral steroids led to sustained disease remission. To our knowledge, this is the first case of isolated ocular LP in a child.

摘要

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