Effect of an antioxydant cream versus placebo in patients with vitiligo in association with excimer laser. A pilot randomized, investigator-blinded, and half-side comparison trial.

The aim of this study was to evaluate the combined effect of excimer laser and a topical antioxidant in the treatment for vitiligo. The study was conducted in a single blinded design on 10 vitiligo patients with symmetrical vitiligo lesions treated with the active antioxidant or a placebo that were irradiated with an excimer laser. Results have shown that the lesions treated with the active cream achieved earlier regimentation compared to the placebo. The use of a cream containing antioxidants may improve the results of excimer laser treatment in patients with vitiligo.