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人类免疫缺陷病毒感染相关心脏病

Human Immunodeficiency Virus Infection-Related Heart Disease.

作者信息

Pham Thuy Van, Torres Mercedes

机构信息

Department of Emergency Medicine, University of Maryland School of Medicine, 110 South Paca Street, Sixth Floor, Suite 200, Baltimore, MD 21201, USA.

Department of Emergency Medicine, University of Maryland School of Medicine, 110 South Paca Street, Sixth Floor, Suite 200, Baltimore, MD 21201, USA.

出版信息

Emerg Med Clin North Am. 2015 Aug;33(3):613-22. doi: 10.1016/j.emc.2015.04.009. Epub 2015 Jun 10.

Abstract

Human immunodeficiency virus (HIV) infection and antiretroviral medications are independent risk factors for cardiovascular disease. In the pre-antiretroviral therapy (ART) era, HIV-infected patients had increased morbidity and mortality from opportunistic infections; in the post-ART era, these patients are at increased risk of chronic diseases such as acute coronary syndrome, coronary artery disease, cardiac arrhythmias, and cardiomyopathy. They may present with vague symptoms such as weakness, dyspnea, or fatigue as the initial presentation of their cardiovascular disease. An overview of the clinical presentation, workup, management, and treatment of different cardiovascular disease is provided in this article.

摘要

人类免疫缺陷病毒(HIV)感染和抗逆转录病毒药物是心血管疾病的独立危险因素。在抗逆转录病毒治疗(ART)时代之前,HIV感染患者因机会性感染导致发病率和死亡率增加;在ART时代之后,这些患者患急性冠状动脉综合征、冠状动脉疾病、心律失常和心肌病等慢性病的风险增加。他们可能以虚弱、呼吸困难或疲劳等模糊症状作为心血管疾病的初始表现。本文提供了不同心血管疾病的临床表现、检查、管理和治疗概述。

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