昆虫中微小RNA对生理过程的调控
Regulation of physiological processes by microRNAs in insects.
作者信息
Lucas Keira J, Zhao Bo, Liu Shiping, Raikhel Alexander S
机构信息
Department of Entomology, University of California Riverside CA 92521, USA ; Graduate Program in Genetics, Genomics and Bioinformatics, University of California Riverside CA 92521, USA.
Department of Entomology, University of California Riverside CA 92521, USA ; Institute for Integrative Genome Biology, University of California Riverside CA 92521, USA.
出版信息
Curr Opin Insect Sci. 2015 Oct 1;11:1-7. doi: 10.1016/j.cois.2015.06.004.
MicroRNAs (miRNAs) are small non-coding RNAs that function in gene regulatory processes in plants and animals by targeting sites within messenger RNA. In insects, miRNAs have been shown to regulate a variety of physiological processes throughout insect development, including molting, metamorphosis, oogenesis, embryogenesis, behavior and host-pathogen interactions. The roles of miRNAs in the model organism, , have been studied extensively due to the conserved nature of miRNA function among highly divergent species. However, seeking to understand miRNA function in non-drosophilid insect species has become a growing trend in insect science. Here, we highlight the recent discoveries regarding miRNA function in insect physiology and development.
微小RNA（miRNA）是一类小的非编码RNA，通过靶向信使RNA中的位点在植物和动物的基因调控过程中发挥作用。在昆虫中，miRNA已被证明在昆虫发育的各个生理过程中发挥调节作用，包括蜕皮、变态、卵子发生、胚胎发生、行为以及宿主-病原体相互作用。由于miRNA功能在高度分化的物种间具有保守性，因此在模式生物果蝇中对miRNA的作用进行了广泛研究。然而，试图了解非果蝇类昆虫物种中miRNA的功能已成为昆虫科学领域日益增长的趋势。在此，我们重点介绍有关miRNA在昆虫生理和发育方面功能的最新发现。
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