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使用自膨式覆膜金属支架进行内镜超声引导下肝脓肿引流的临床结果(附视频)

Clinical Outcome of Endoscopic Ultrasound-Guided Liver Abscess Drainage Using Self-Expandable Covered Metallic Stent (with Video).

作者信息

Ogura Takeshi, Masuda Daisuke, Saori Onda, Wataru Takagi, Sano Tatsushi, Okuda Atsushi, Miyano Akira, Kitano Masayuki, Abdel-Aal Usama M, Takeuchi Toshihisa, Fukunishi Shinya, Higuchi Kazuhide

机构信息

2nd Department of Internal Medicine, Osaka Medical College, 1-1 Daigakuchou, Takatsukishi, Osaka, 464-8681, Japan.

Department of Gastroenterology and Hepatology, Kinki University Faculty of Medicine, Osaka-sayama, Japan.

出版信息

Dig Dis Sci. 2016 Jan;61(1):303-8. doi: 10.1007/s10620-015-3841-3. Epub 2015 Aug 9.

Abstract

BACKGROUND

Percutaneous drainage (PCD) is now the first-line drainage method for liver abscess because of its minimal invasiveness and high technical success rate. However, this procedure has several disadvantages, such as extra-drainage and self-tube removal. Recently, EUS-guided liver abscess drainage (EUS-AD) has been developed. However, only a few reports of EUS-AD have been reported. In addition, the clinical benefits of PCD and EUS-AD have not been reported.

AIMS

In the present study, the safety and feasibility of EUS-AD using fully covered SEMS (FCSEMS) and the clinical outcomes of EUS-AD and PCD were examined retrospectively.

METHODS

Twenty-seven consecutive patients who underwent PCD or EUS-AD between April 2012 and April 2015 were included in this study. EUS-AD was performed using FCSEMS. In addition, to prevent stent migration, 7-Fr pig tail plastic stent was placed within FCSEMS.

RESULTS

Technical success was achieved in all patients of both groups. Clinical success was 100 % in the EUS-AD group although it was 89 % in PCD group (P = 034). Three adverse events were seen in the PCD group (self-tube removal n = 1, tube migration n = 2), but no adverse events were seen in the EUS-AD group. The median hospital stay was significantly shorter in the EUS-AD group than in the PCD group (21 vs 41 days, P = 0.03).

CONCLUSION

Because of the short hospital stay, the high clinical success rate, and the low adverse event rate compared to PCD, EUS-AD has potential as a first-line treatment for liver abscess.

摘要

背景

经皮引流(PCD)因其微创性和高技术成功率,现已成为肝脓肿的一线引流方法。然而,该操作存在一些缺点,如额外引流和自行拔管。近年来,已开展了超声内镜引导下肝脓肿引流(EUS-AD)。然而,关于EUS-AD的报道较少。此外,PCD和EUS-AD的临床益处尚未见报道。

目的

在本研究中,回顾性研究了使用全覆膜自膨式金属支架(FCSEMS)进行EUS-AD的安全性和可行性,以及EUS-AD和PCD的临床结果。

方法

本研究纳入了2012年4月至2015年4月期间连续接受PCD或EUS-AD治疗的27例患者。使用FCSEMS进行EUS-AD。此外,为防止支架移位,在FCSEMS内置入7F猪尾塑料支架。

结果

两组所有患者均取得技术成功。EUS-AD组临床成功率为100%,而PCD组为89%(P = 0.34)。PCD组出现3例不良事件(自行拔管1例,导管移位2例),而EUS-AD组未出现不良事件。EUS-AD组的中位住院时间明显短于PCD组(21天对41天,P = 0.03)。

结论

与PCD相比,EUS-AD住院时间短、临床成功率高、不良事件发生率低,有潜力作为肝脓肿的一线治疗方法。

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