Purohit Manju Raj, Sharma Megha, Rosales-Klintz Senia, Lundborg Cecilia Stålsby
Department of Pathology, R. D. Gardi Medical College, Ujjain, India.
Central Clinical Laboratory, Ujjain Charitable Trust Hospital and Research Centre, Ujjain, India.
BMC Infect Dis. 2015 Aug 11;15:322. doi: 10.1186/s12879-015-1037-2.
Delay in diagnosis is one of the most important factors for the control of tuberculosis (TB) in endemic countries like India. As laboratory diagnosis is the mainstay for identification of active disease, we aim to explore and understand the opinions of medical doctors about the laboratory diagnosis of TB in Ujjain, India.
Sixteen qualified specialist medical doctors from Ujjain were purposefully selected for the study. Individual interviews with the doctors (13 men and 3 women), were conducted. As one interview could not be completed, data from 15 interviews were analyzed using manifest and latent content analysis.
Based on perception of the doctors, the theme; 'challenges and need for the laboratory diagnosis of TB' emerged from the following subthemes: (i) Relationship between basic element of the TB diseases process such as 'Symptoms prior to diagnoses' and 'Clinical characteristics of TB', which were not specific enough to diagnose TB (ii) The prevailing conditions such as lack of explicit diagnostic tools, lead to the doctors using the 'multiple tests' or 'empiric treatment' approach (iii) The doctors proposed that there is a need for access to a rapid, single and simple diagnostic test, and a need for awareness and knowledge of the practitioners regarding specific TB investigations, and early referral to improve the situation at resource-limited settings.
The medical specialists use a 'multiple test' or 'empiric treatment' approach to diagnose TB. According to the participants, there is a low dependence and uptake of the available laboratory TB investigations by medical practitioners. There is an urgent need to have a specific, simple and reliable test, and a protocol, to improve diagnosis of TB and to prevent development of resistant TB.
在印度等结核病流行国家,诊断延迟是控制结核病的最重要因素之一。由于实验室诊断是识别活动性疾病的主要手段,我们旨在探讨并了解印度乌贾因地区医生对结核病实验室诊断的看法。
从乌贾因地区有目的地挑选了16名合格的专科医生参与研究。对这些医生(13名男性和3名女性)进行了个人访谈。由于有一次访谈未完成,因此使用显性和隐性内容分析法对15次访谈的数据进行了分析。
基于医生的认知,“结核病实验室诊断的挑战与需求”这一主题源自以下子主题:(i)结核病病程基本要素之间的关系,如“诊断前症状”和“结核病的临床特征”,这些特征不足以确诊结核病;(ii)当前状况,如缺乏明确的诊断工具,导致医生采用“多项检查”或“经验性治疗”方法;(iii)医生们提出,需要一种快速、单一且简单的诊断测试,从业者需要了解和掌握特定的结核病检查知识,并尽早转诊,以改善资源有限地区的状况。
医学专家采用“多项检查”或“经验性治疗”方法来诊断结核病。根据参与者的说法,医生对现有的结核病实验室检查的依赖程度和使用率较低。迫切需要一种特定、简单且可靠的检测方法和方案,以改善结核病的诊断并预防耐药结核病的发生。