Rasubala Linda, Pernapati Lavanya, Velasquez Ximena, Burk James, Ren Yan-Fang
Department of General Dentistry, University of Rochester Eastman Institute for Oral Health, 625 Elmwood Avenue, Rochester, New York, 14620, United States of America.
PLoS One. 2015 Aug 14;10(8):e0135957. doi: 10.1371/journal.pone.0135957. eCollection 2015.
Prescription Drug Monitoring Programs (PDMP) are statewide databases that collect data on prescription of controlled substances. New York State mandates prescribers to consult the PDMP registry before prescribing a controlled substance such as opioid analgesics. The effect of mandatory PDMP on opioid drug prescriptions by dentists is not known. This study investigates the impact of mandatory PDMP on frequency and quantity of opioid prescriptions by dentists in a dental urgent care center. Based on the sample size estimate, we collected patient records of a 3-month period before and two consecutive 3-month periods after the mandatory PDMP implementation and analyzed the data on number of visits, treatment types and drug prescriptions using Chi-square tests. For patients who were prescribed pain medications, 452 (30.6%), 190 (14.1%), and 140 (9.6%) received opioid analgesics in the three study periods respectively, signifying a statistically significant reduction in the number of opioid prescriptions after implementation of the mandatory PDMP (p<0.05). Total numbers of prescribed opioid pills in a 3-month period decreased from 5096 to 1120, signifying a 78% reduction in absolute quantity. Prescriptions for non-opioid analgesics acetaminophen increased during the same periods (p<0.05). We conclude that the mandatory PDMP significantly affected the prescription pattern for pain medications by dentists. Such change in prescription pattern represents a shift towards the evidence-based prescription practices for acute postoperative pain.
处方药监测计划(PDMP)是收集受控物质处方数据的全州性数据库。纽约州要求开处方者在开具诸如阿片类镇痛药等受控物质之前查阅PDMP登记册。强制性PDMP对牙医开具阿片类药物处方的影响尚不清楚。本研究调查了强制性PDMP对牙科紧急护理中心牙医开具阿片类药物处方的频率和数量的影响。根据样本量估计,我们收集了强制性PDMP实施前3个月以及实施后连续两个3个月期间的患者记录,并使用卡方检验分析了就诊次数、治疗类型和药物处方数据。对于开具了止痛药物的患者,在三个研究期间分别有452名(30.6%)、190名(14.1%)和140名(9.6%)接受了阿片类镇痛药,这表明实施强制性PDMP后阿片类药物处方数量有统计学意义的减少(p<0.05)。三个月期间开具的阿片类药丸总数从5096降至1120,绝对数量减少了78%。同期非阿片类镇痛药对乙酰氨基酚的处方量增加(p<0.05)。我们得出结论,强制性PDMP显著影响了牙医开具止痛药物的处方模式。这种处方模式的变化代表了向基于证据的急性术后疼痛处方实践的转变。