Otte M, Andree C, Hagouan M, Richrath P, Abu-Ghazaleh A, Munder B
Plastische und Ästhetische Chirurgie, SANA Klinik Gerresheim, Düsseldorf.
Handchir Mikrochir Plast Chir. 2015 Aug;47(4):222-7. doi: 10.1055/s-0034-1398662. Epub 2015 Aug 19.
Autologous breast reconstruction is becoming increasingly important, especially in light of the increased rates of prophylactic mastectomies with BRCA mutations. Regarding the indications and complications between free TRAM and free DIEP flaps for autologous breast reconstruction the current data is not clear.
All patients who received an autologous breast reconstruction between January 2010 and January 2014 using free DIEP or free MS-2-TRAM flaps were included in the study. The choice of flap between DIEP and MS-2-TRAM was performed by a standardised algorithm with preoperative CT angiography, intraoperative evaluation of the flap perfusion and Doppler detection. The analysis took into account partial flap necrosis <20% and >20%), complete flap loss, flap necrosis and surgical revision of the anastomosis.
The study considered 362 women who received a total of 419 free flaps for breast reconstruction. 66 patients received a bilateral reconstruction (52 double DIEPS, 9 DIEP and MS2 TRAM and 5 double MS2 TRAMs). The total flap loss was 0.24%. Partial necrosis <20% occurred in 0.72% (DIEP 0.82%, MS2 TRAM 0%), partial necrosis >20% in 0.72% (DIEP 0.69% MS2 TRAM 0.98%). One DIEP flap was lost (0.24%). After implementing our protocol the rate of MS-2-Tram flaps could be reduced to 10-15% of all autologous breast reconstruction procedures as compared to the years before.
Through the application of the presented algorithm for breast reconstruction with free DIEP flap, such surgery is a safe treatment option if it is done at high frequency in a microsurgical centre. Flap loss and complications are not increased compared to MS2 TRAM flaps. The decision for the selection of the appropriate flap for breast reconstruction should be based on the presented algorithm in order to achieve secure and reproducible results.
自体乳房重建变得越来越重要,尤其是鉴于携带BRCA突变的预防性乳房切除术的发生率增加。关于游离横腹直肌肌皮瓣(TRAM)和游离腹壁下动脉穿支皮瓣(DIEP)用于自体乳房重建的适应症和并发症,目前的数据尚不清楚。
本研究纳入了2010年1月至2014年1月期间所有使用游离DIEP或游离MS-2-TRAM皮瓣进行自体乳房重建的患者。DIEP和MS-2-TRAM皮瓣的选择通过标准化算法进行,包括术前CT血管造影、术中皮瓣灌注评估和多普勒检测。分析考虑了皮瓣部分坏死(<20%和>20%)、皮瓣完全坏死、皮瓣坏死以及吻合口的手术修复。
该研究纳入了362名接受了总共419次游离皮瓣乳房重建的女性。66名患者接受了双侧重建(52例双侧DIEP、9例DIEP和MS2 TRAM以及5例双侧MS2 TRAM)。皮瓣总坏死率为0.24%。部分坏死<20%的发生率为0.72%(DIEP为0.82%,MS2 TRAM为0%),部分坏死>20%的发生率为0.72%(DIEP为0.69%,MS2 TRAM为0.98%)。有1例DIEP皮瓣坏死(0.24%)。实施我们的方案后,与之前几年相比,MS-2-TRAM皮瓣的使用比例可降至所有自体乳房重建手术的10%-15%。
通过应用所提出的游离DIEP皮瓣乳房重建算法,如果在显微外科中心高频进行此类手术,它是一种安全的治疗选择。与MS2 TRAM皮瓣相比,皮瓣坏死和并发症并未增加。为实现安全且可重复的结果,应基于所提出的算法来决定选择合适的皮瓣进行乳房重建。