Kauffman Yardlee S, Schroeder Allison E, Witt Daniel M
Department of Pharmacy Practice and Administration, Philadelphia College of Pharmacy, Philadelphia, Pennsylvania.
Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.
Pharmacotherapy. 2015 Aug;35(8):740-7. doi: 10.1002/phar.1616.
The specific reasons underlying nonadherence to monitoring the international normalized ratio (INR) from the patient's perspective have not been formally studied. Understanding why patients do or do not adhere has the potential to reveal useful targets for improving adherence to INR monitoring or alternative treatment strategies. The objective of this study was to gain further insight into INR monitoring nonadherence from the patient's perspective.
This qualitative study was conducted among members of Kaiser Permanente Colorado; patients were characterized as adherent or nonadherent and recruited from the Clinical Pharmacy Anticoagulation and Anemia Service to participate in an individual interview. Qualitative analysis was performed to identify emerging themes using an inductive approach. Demographic data were summarized using descriptive statistics.
Patients were primarily white and employed with a mean age of 61.3 years. Perspectives and experiences were similar for all interviewed patients regardless of classification as adherent or nonadherent. The most common themes were the desire for INR monitoring to be inexpensive, convenient, and accessible; finding reassurance with INR monitoring; and a preference for interacting with the same group of prescribers, pharmacists, and phlebotomists.
The following strategies to improve adherence to INR testing are suggested: (i) assign anticoagulation providers to work with the same patients consistently; (ii) provide formal INR reminders; (iii) avoid harsh language or lecturing patients following missed INR tests; (iv) reinforce the clinical and psychological utility of INR results; and (v) facilitate access to INR testing. Adopting these strategies into clinical practice can support the patient-clinician relationship and empower patients to be more engaged in their health care.
从患者角度来看,国际标准化比值(INR)监测不依从的具体原因尚未得到正式研究。了解患者依从或不依从的原因可能会揭示出改善INR监测依从性或替代治疗策略的有用目标。本研究的目的是从患者角度进一步深入了解INR监测不依从的情况。
本定性研究在科罗拉多州凯撒医疗机构的成员中进行;将患者分为依从或不依从两类,并从临床药学抗凝与贫血服务部门招募患者参与个人访谈。采用归纳法进行定性分析以确定新出现的主题。使用描述性统计方法总结人口统计学数据。
患者主要为白人,有工作,平均年龄61.3岁。所有接受访谈的患者,无论分类为依从或不依从,其观点和经历都相似。最常见的主题是希望INR监测价格低廉、方便且易于获得;通过INR监测获得安心感;以及倾向于与同一组开处方者、药剂师和采血员互动。
建议采取以下策略来提高INR检测的依从性:(i)安排抗凝治疗提供者持续与同一批患者合作;(ii)提供正式的INR提醒;(iii)在患者错过INR检测后避免使用严厉语言或教训患者;(iv)强化INR结果的临床和心理效用;(v)便利进行INR检测。将这些策略应用于临床实践可以支持患者与临床医生的关系,并使患者更积极地参与自身医疗保健。