[Clinical study of anti-Mullerian hormone in prediction of ovarian aging].
作者信息
Gao Lihong, Cai Wenwei, Zhu Qin, Li Yongxiang, Jin Qianyan, Zhang Meiguang, Cai Yingru, Zhou Zhiting, Wu Xiaojie
机构信息
Department of Obstetrics and Gynecology, Jiaxing Maternity and Child Health Care Hospital, Jiaxing 314000, China.
314000 Department of Obstetrics and Gynecology, Jiaxing University; Email:
出版信息
Zhonghua Fu Chan Ke Za Zhi. 2015 May;50(5):352-5.
OBJECTIVE
To explore the serum anti-Mullerian hormone (AMH) level in women of childbearing age with normal menstrual cycles.
METHODS
A total of 1 423 women with regular menstrual cycles were selected and divided into 5 groups according to their ages, i.e. ≤ 25, 26-30, 31-35, 36-40, ≥ 41 years. Their serum levels of AMH were measured, and the relationship between AMH and age was analyzed.
RESULTS
The serum AMH levels of 5 groups according to ages (≤ 25, 26-30, 31-35, 36-40, ≥ 41 years) were 3.62, 3.10, 2.27, 1.07, 0.45 µg/L, respectively. The comparison of serum AMH levels in different age groups had significant difference (P < 0.01). Serum AMH level declined with increasing age, and dropped significantly after 36. The serum AMH level and age showed a negative correlation with significant difference (r = -0.374, P < 0.01). Quadratic regression of logAMH proximally reflected the relationship between AMH and age.
CONCLUSION
AMH determination for women of childbearing age could provide reference for the evaluation of ovarian function.
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