Cerpa F, Cáceres D, Romero-Dapueto C, Giugliano-Jaramillo C, Pérez R, Budini H, Hidalgo V, Gutiérrez T, Molina J, Keymer J
Servicio de Medicina Física y Rehabilitación, Clínica Alemana de Santiago, Santiago, Chile.
Escuela de Kinesiología, Universidad del Desarrollo, Santiago, Chile.
Open Respir Med J. 2015 Jun 26;9:104-11. doi: 10.2174/1874306401509010104. eCollection 2015.
The normal physiology of conditioning of inspired gases is altered when the patient requires an artificial airway access and an invasive mechanical ventilation (IMV). The endotracheal tube (ETT) removes the natural mechanisms of filtration, humidification and warming of inspired air. Despite the noninvasive ventilation (NIMV) in the upper airways, humidification of inspired gas may not be optimal mainly due to the high flow that is being created by the leakage compensation, among other aspects. Any moisture and heating deficit is compensated by the large airways of the tracheobronchial tree, these are poorly suited for this task, which alters mucociliary function, quality of secretions, and homeostasis gas exchange system. To avoid the occurrence of these events, external devices that provide humidification, heating and filtration have been developed, with different degrees of evidence that support their use.
当患者需要人工气道通路和有创机械通气(IMV)时,吸入气体调节的正常生理过程会发生改变。气管内插管(ETT)消除了吸入空气的自然过滤、加湿和加热机制。尽管上呼吸道存在无创通气(NIMV),但吸入气体的加湿可能并不理想,主要是由于泄漏补偿产生的高流量等因素。气管支气管树的大气道会补偿任何水分和热量不足,但它们并不适合这项任务,这会改变黏液纤毛功能、分泌物质量和气体交换系统的稳态。为避免这些情况的发生,已开发出提供加湿、加热和过滤功能的外部设备,并有不同程度的证据支持其使用。