Rubinsky Anna D, Chen Cheng, Batki Steven L, Williams Emily C, Harris Alex H S
Veterans Affairs (VA) Substance Use Disorder Quality Enhancement Research Initiative (SUD QUERI), VA Palo Alto Health Care System, 795 Willow Road (MPD 152), Menlo Park, CA 94025, USA; Center for Innovation to Implementation (Ci2i), Health Services Research and Development, VA Palo Alto Health Care System, 795 Willow Road (MPD 152), Menlo Park, CA 94025, USA.
Center for Innovation to Implementation (Ci2i), Health Services Research and Development, VA Palo Alto Health Care System, 795 Willow Road (MPD 152), Menlo Park, CA 94025, USA.
J Psychiatr Res. 2015 Oct;69:150-7. doi: 10.1016/j.jpsychires.2015.07.016. Epub 2015 Jul 22.
Patients with alcohol use disorder (AUD) and another co-occurring psychiatric disorder are a vulnerable population with high symptom severity. Such patients may benefit from a full arsenal of treatment options including pharmacotherapy. Receipt of AUD pharmacotherapy is generally very low despite recommendations that it be made available to every patient with AUD, including those with co-occurring disorders. Little is known about pharmacotherapy rates for AUD compared to other psychiatric disorders among patients with dual diagnoses. This study compared rates of pharmacotherapy for AUD to those for non-substance use psychiatric disorders and tobacco use disorder among patients with dual diagnoses in the U.S. Veterans Affairs (VA) healthcare system. VA data were used to identify patients with AUD and another psychiatric disorder in fiscal year 2012, and to estimate the proportion receiving pharmacotherapy for AUD and for each comorbid condition. Among subsets of patients with AUD and co-occurring schizophrenic, bipolar, posttraumatic stress or major depressive disorder, receipt of medications for AUD ranged from 7% to 11%, whereas receipt of medications for the comorbid disorder ranged from 69% to 82%. Among patients with AUD and co-occurring tobacco use disorder, 6% received medication for their AUD and 34% for their tobacco use disorder. Among patients with dual diagnoses, rates of pharmacotherapy for AUD were far lower than those for the comorbid disorders and contrary to evidence that medications for AUD are effective. Additional system-wide implementation efforts to identify and address patient- and provider-level barriers are needed to increase AUD pharmacotherapy in this high-need population.
患有酒精使用障碍(AUD)且同时患有另一种精神疾病的患者是一个症状严重程度高的脆弱群体。这类患者可能会从包括药物治疗在内的全套治疗方案中受益。尽管有建议称应向每一位患有AUD的患者,包括那些同时患有其他疾病的患者提供AUD药物治疗,但实际接受该治疗的比例普遍非常低。与其他双重诊断患者中的精神疾病相比,关于AUD药物治疗率的了解甚少。本研究比较了美国退伍军人事务部(VA)医疗系统中双重诊断患者的AUD药物治疗率与非物质使用性精神疾病和烟草使用障碍的药物治疗率。利用VA数据识别出2012财年患有AUD和另一种精神疾病的患者,并估计接受AUD药物治疗以及每种共病情况药物治疗的比例。在患有AUD并同时患有精神分裂症、双相情感障碍、创伤后应激障碍或重度抑郁症的患者亚组中,接受AUD药物治疗的比例为7%至11%,而接受共病疾病药物治疗的比例为69%至82%。在患有AUD并同时患有烟草使用障碍的患者中,6%的患者接受了AUD药物治疗,34%的患者接受了烟草使用障碍药物治疗。在双重诊断患者中,AUD药物治疗率远低于共病疾病的治疗率,这与AUD药物有效这一证据相悖。需要在全系统开展更多实施工作,以识别并消除患者和医疗服务提供者层面的障碍,从而提高这一高需求人群的AUD药物治疗率。