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可塑型植入物挽救技术:马尔卡希挽救手术后的感染结果以及用可塑型假体替换感染的可膨胀阴茎假体后的情况

The Malleable Implant Salvage Technique: Infection Outcomes after Mulcahy Salvage Procedure and Replacement of Infected Inflatable Penile Prosthesis with Malleable Prosthesis.

作者信息

Gross Martin S, Phillips Elizabeth A, Balen Alejandra, Eid J Francois, Yang Christopher, Simon Ross, Martinez Daniel, Carrion Rafael, Perito Paul, Levine Laurence, Greenfield Jason, Munarriz Ricardo

机构信息

Boston University Medical Center, Boston, Massachusetts.

Boston University Medical Center, Boston, Massachusetts.

出版信息

J Urol. 2016 Mar;195(3):694-7. doi: 10.1016/j.juro.2015.08.091. Epub 2015 Sep 3.

Abstract

PURPOSE

Since its introduction in 1996 Mulcahy salvage has significantly improved outcomes for the removal and replacement of infected inflatable penile prostheses. Long-term followup data of Mulcahy salvage show an infection-free rate of 82%. A multicenter retrospective analysis of the malleable implant salvage technique was conducted to assess infection outcomes and the feasibility of conversion from malleable device back to inflatable penile prosthesis.

MATERIALS AND METHODS

This is a retrospective, institutional review board exempt, multi-institution study of 58 patients who underwent Mulcahy salvage with inflatable penile prosthesis removal and replacement with malleable prosthesis. Patient operative notes and charts were extensively reviewed to compile study data.

RESULTS

Between 2002 and 2014 a total of 58 patients underwent infected inflatable penile prosthesis removal and replacement with a malleable prosthesis via Mulcahy salvage. Of these patients 54 (93%) have remained infection-free postoperatively. Average patient age was 56.4 years and average operative time was 148 minutes. Postoperative followup (as of May 2015) ranged from 1 month to 84 months. Of the 54 patients 37 retained the malleable prosthesis and 17 (31%) subsequently underwent replacement with an inflatable penile prosthesis. This occurred on average 6.7 months after Mulcahy salvage. Four patients had persistent infection after Mulcahy salvage with the malleable prosthesis and underwent explantation.

CONCLUSIONS

This retrospective analysis of Mulcahy salvage procedure and replacement of inflatable penile prosthesis with malleable prosthesis shows a high infection-free rate. Additionally, 17 of the 54 patients who remained infection-free were able to successfully undergo subsequent removal of the malleable prosthesis and replacement with an inflatable penile prosthesis. Further prospective studies are needed to compare salvage with malleable vs inflatable penile prosthesis.

摘要

目的

自1996年引入以来,Mulcahy挽救手术显著改善了感染性可膨胀阴茎假体取出和更换后的治疗效果。Mulcahy挽救手术的长期随访数据显示无感染率为82%。我们对可弯曲阴茎假体挽救技术进行了一项多中心回顾性分析,以评估感染治疗效果以及从可弯曲装置转换回可膨胀阴茎假体的可行性。

材料与方法

这是一项回顾性、经机构审查委员会豁免的多机构研究,研究对象为58例行Mulcahy挽救手术、取出可膨胀阴茎假体并更换为可弯曲假体的患者。对患者的手术记录和病历进行了广泛审查以收集研究数据。

结果

2002年至2014年期间,共有58例患者通过Mulcahy挽救手术取出感染的可膨胀阴茎假体并更换为可弯曲假体。这些患者中,54例(93%)术后无感染。患者平均年龄为56.4岁,平均手术时间为148分钟。术后随访(截至2015年5月)时间为1个月至84个月。54例患者中,37例保留了可弯曲假体,17例(31%)随后更换为可膨胀阴茎假体。这平均发生在Mulcahy挽救手术后6.7个月。4例患者在Mulcahy挽救手术植入可弯曲假体后仍持续感染,随后进行了取出手术。

结论

这项对Mulcahy挽救手术及用可弯曲假体替代可膨胀阴茎假体的回顾性分析显示无感染率很高。此外,54例无感染患者中有17例能够成功地随后取出可弯曲假体并更换为可膨胀阴茎假体。需要进一步进行前瞻性研究以比较可弯曲阴茎假体与可膨胀阴茎假体的挽救效果。

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