预防性HIV疫苗在中国的潜在影响：多省份建模合作的结果与益处

Harmon Thomas, Guo Wei, Stover John, Wu Zunyou, Kaufman Joan, Schneider Kammerle, Liu Li, Feng Liao, Schwartländer Bernard

International AIDS Vaccine Initiative, 125 Broad St., 9th Floor, New York, NY 10004, USA.

Chinese National Center for AIDS/STD Control and Prevention (NCAIDS), Beijing 102206, China.

Vaccines (Basel). 2015 Jan 5;3(1):1-19. doi: 10.3390/vaccines3010001.

China's commitment to implementing established and emerging HIV/AIDS prevention and control strategies has led to substantial gains in terms of access to antiretroviral treatment and prevention services, but the evolving and multifaceted HIV/AIDS epidemic in China highlights the challenges of maintaining that response. This study presents modeling results exploring the potential impact of HIV vaccines in the Chinese context at varying efficacy and coverage rates, while further exploring the potential implications of vaccination programs aimed at reaching populations at highest risk of HIV infection. A preventive HIV vaccine would add a powerful tool to China's response, even if not 100% efficacious or available to the full population.

中国致力于实施既定的和新出现的艾滋病毒/艾滋病预防与控制策略，在获得抗逆转录病毒治疗和预防服务方面取得了显著成效，但中国不断演变且多层面的艾滋病毒/艾滋病疫情凸显了维持这一应对措施所面临的挑战。本研究展示了模型结果，探讨了在不同效力和覆盖率情况下，艾滋病毒疫苗在中国可能产生的影响，同时进一步探讨了旨在覆盖艾滋病毒感染风险最高人群的疫苗接种计划的潜在影响。即使预防性艾滋病毒疫苗并非100%有效或无法覆盖全体人口，它也将为中国的应对措施增添一个有力工具。