Analytical applications of nanoparticles in MALDI-MS for bioanalysis.

作者信息

Kailasa Suresh Kumar, D'souza Stephanie, Wu Hui-Fen

机构信息

Department of Applied Chemistry, S. V. National Institute of Technology, Surat, Gujarat 395007, India.

Department of Chemistry, Medical Science & Technology, Doctoral Degree Program of Marine Biotechnoloty, Nanoscience & Nanotechnology, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan.

出版信息

Bioanalysis. 2015;7(17):2265-76. doi: 10.4155/bio.15.149. Epub 2015 Sep 10.

Recently, the rapid development of nanotechnology has enabled the analytical community to integrate processes with MALDI-MS for the analysis of various biomolecules. This article presents the recent progress on nanomaterials as extracting probes in single-drop microextraction, in liquid-liquid microextraction and as affinity probes for the enrichment of trace level biomolecules prior to their identification by MALDI-MS.