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物理气相沉积技术制备的抗菌TiAgN薄膜的特性

The Characteristics of an Antibacterial TiAgN Thin Film Coated by Physical Vapor Deposition Technique.

作者信息

Kang Byeong-Mo, Jeong Woon-Jo, Park Gye-Choon, Yoon Dong-Joo, Ahn Ho-Geun, Lim Yeong-Seog

出版信息

J Nanosci Nanotechnol. 2015 Aug;15(8):6020-3. doi: 10.1166/jnn.2015.10417.

Abstract

In this work, we found the characteristics of an antibacterial TiAgN thin film coated on the pure titanium specimen via the physical vapor deposition process (PVD). TiAgN thin films were coated using TiAg alloy targets by arc ion plating method. Changing the process parameters, the surface analysis of TiAgN thin film was observed by FE-SEM and the force of adhesion was measured with Scratch Tester. The proliferation of human gingival fibroblast (HGF) cells was examined by XTT test assay and the antibacterial properties were investigated by culturing Streptococus Mutans (KCTC 3065) using paper disk techniques. At the result of experiment, cytotoxic effects were not found and the antibacterial effects against Streptococus Mutans were appeared over 5 wt% TiAgN specimens.

摘要

在本研究中,我们通过物理气相沉积工艺(PVD)在纯钛样本上发现了一种抗菌TiAgN薄膜的特性。采用电弧离子镀法,使用TiAg合金靶材制备TiAgN薄膜。通过改变工艺参数,利用场发射扫描电子显微镜(FE-SEM)对TiAgN薄膜进行表面分析,并使用划痕测试仪测量附着力。通过XTT测试法检测人牙龈成纤维细胞(HGF)的增殖情况,并采用纸片扩散法培养变形链球菌(KCTC 3065)来研究抗菌性能。实验结果表明,未发现细胞毒性作用,且含TiAgN超过5 wt%的样本对变形链球菌具有抗菌作用。

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