在边缘系统疾病的鉴别诊断中识别自身免疫介导的脑炎。
Recognizing Autoimmune-Mediated Encephalitis in the Differential Diagnosis of Limbic Disorders.
作者信息
da Rocha A J, Nunes R H, Maia A C M, do Amaral L L F
机构信息
From the Division of Neuroradiology (A.J.d.R., R.H.N., A.C.M.M., L.L.F.d.A.), Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil Division of Neuroradiology (A.J.d.R., R.H.N., A.C.M.M.), Fleury Medicina e Saúde, São Paulo, Brazil
From the Division of Neuroradiology (A.J.d.R., R.H.N., A.C.M.M., L.L.F.d.A.), Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil Division of Neuroradiology (A.J.d.R., R.H.N., A.C.M.M.), Fleury Medicina e Saúde, São Paulo, Brazil Research Fellow, University of North Carolina (R.H.N.), Chapel Hill, North Carolina.
出版信息
AJNR Am J Neuroradiol. 2015 Dec;36(12):2196-205. doi: 10.3174/ajnr.A4408. Epub 2015 Sep 17.
Limbic encephalitis is far more common than previously thought. It is not always associated with cancer, and it is potentially treatable. Autoantibodies against various neuronal cell antigens may arise independently or in association with cancer and cause autoimmune damage to the limbic system. Neuroimaging plays a key role in the management of patients with suspected limbic encephalitis by supporting diagnosis and excluding differential possibilities. This article describes the main types of autoimmune limbic encephalitis and its mimic disorders, and emphasizes their major imaging features.
边缘叶性脑炎比之前认为的更为常见。它并不总是与癌症相关，且具有潜在的可治疗性。针对各种神经元细胞抗原的自身抗体可能独立出现或与癌症相关，并对边缘系统造成自身免疫性损伤。神经影像学在疑似边缘叶性脑炎患者的管理中发挥着关键作用，有助于支持诊断并排除鉴别诊断的可能性。本文描述了自身免疫性边缘叶性脑炎的主要类型及其模仿性疾病，并强调了它们的主要影像学特征。
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